ID   K9G0B3_PEND2            Unreviewed;       602 AA.
AC   K9G0B3;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   SubName: Full=Sorting nexin-41 {ECO:0000313|EMBL:EKV08333.1};
GN   ORFNames=PDIG_69080 {ECO:0000313|EMBL:EKV08333.1};
OS   Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV08333.1, ECO:0000313|Proteomes:UP000009882};
RN   [1] {ECO:0000313|Proteomes:UP000009882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX   PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA   Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA   Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT   "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT   postharvest pathogen of citrus.";
RL   BMC Genomics 13:646-646(2012).
CC   -!- SUBCELLULAR LOCATION: Endosome membrane
CC       {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004170}.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKV08333.1}.
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DR   EMBL; AKCT01000253; EKV08333.1; -; Genomic_DNA.
DR   STRING; 1170229.K9G0B3; -.
DR   eggNOG; KOG2273; Eukaryota.
DR   HOGENOM; CLU_014456_0_0_1; -.
DR   InParanoid; K9G0B3; -.
DR   OMA; CRRMKEV; -.
DR   OrthoDB; 5475877at2759; -.
DR   Proteomes; UP000009882; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR   CDD; cd06867; PX_SNX41_42; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR044106; PX_Snx41/Atg20.
DR   PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR   PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR   Pfam; PF00787; PX; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   3: Inferred from homology;
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009882}.
FT   DOMAIN          94..211
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          220..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          445..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..270
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        448..495
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   602 AA;  66502 MW;  855BF161236AA306 CRC64;
     MWNDEDNNPY GAFDQHESGL SDSLHSAALS PPLYEHDPTP PSSRESSNEP PDYTTHAEDL
     SDPEDDAEFG AASEQYPRKS VYDSRIEQIL YENPEMPILI TEAGKNHEGG GGFIVYTIRT
     ADLEVRRRYS EFASLRQTLV NLHPTLVVPP IPEKHSMADY AAKPTRAKDD MAIIDLRKRM
     LSVFLNRCRR MKEIREDGVW WRFLDPNVSW SEVLSSHPAA SVPKNNLKAP PLDPANPTPA
     HGWLPIPSTS AKLKPRAGTT TVSGIAASPT SPTEPEPPSF SGSEMLGRFP PDARKLSEEE
     LDPYFINFEA STRELELLLQ GNIEKVNRRT LSHLSGLSAD LMELGARYNG FSLSEQSPTV
     AAAIERIGQA ADTSYIETEE LSSALSASFA EPMRESAQFA SVVRGVLRYR VLKRVQQEMT
     RDELSKKKTL LDSLERSELE AKRIEQYLNR TNPHSGVTKP RSQSTSSAIN SEGGNGPVMS
     SDPGFPSTHD NPMSFAPGSQ IGGLRRSDPS VPGSPAHRKS SSGTFVANKI FGRISHAIHG
     FADVDPERTR RDQIGKTKES LIQLEQALEV SEQDVKDASA GVLNDLKRFQ KDKXTPPPLQ
     EL
//