ID   K9GI07_PEND1            Unreviewed;      1350 AA.
AC   K9GI07;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=5-oxo-L-prolinase, putative {ECO:0000313|EMBL:EKV20639.1};
GN   ORFNames=PDIP_14660 {ECO:0000313|EMBL:EKV20639.1};
OS   Penicillium digitatum (strain Pd1 / CECT 20795) (Green mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1170230 {ECO:0000313|EMBL:EKV20639.1, ECO:0000313|Proteomes:UP000009886};
RN   [1] {ECO:0000313|Proteomes:UP000009886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pd1 / CECT 20795 {ECO:0000313|Proteomes:UP000009886};
RX   PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA   Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA   Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT   "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT   postharvest pathogen of citrus.";
RL   BMC Genomics 13:646-646(2012).
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKV20639.1}.
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DR   EMBL; AKCU01000106; EKV20639.1; -; Genomic_DNA.
DR   RefSeq; XP_014537635.1; XM_014682149.1.
DR   GeneID; 26229789; -.
DR   KEGG; pdp:PDIP_14660; -.
DR   HOGENOM; CLU_002157_0_0_1; -.
DR   OrthoDB; 674at2759; -.
DR   Proteomes; UP000009886; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
FT   DOMAIN          11..231
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          251..561
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          574..762
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          783..1317
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1350 AA;  147179 MW;  88A66F89C362AFF8 CRC64;
     MNSAKKTGIS IAIDRGGTFT DCVGNPGTDR LEDDVVVKLL SDDPNNYKDA PLEGIRRILS
     NFTGHDIPRG EPIDTSLIQS IRMGTTVATN ALLERKGEKV ALVVSRGFKD CLEIGNQSRP
     KIFDLAIKRP DVLYEEVIEV DERVTLEDYA EDPQRRTTAT TLREQTQTGD VVIRGLSSEA
     VRILKRPSEE LVRSQLEEAY SRGIKSIAVC LIHGYTFPDH EALVGRIAKD IGFHHVSLSH
     QLMPMIKLVP RTTSACADAY LTPAIKKYIS AFQAGFEGGL GSESVKKQAG AKGASCEFMQ
     SDGGLVDVDQ FSGLRAILSG PAGGVVGYAL TSYDPVSKTP VIGFDMGGTS TDVSRYGSGR
     YEHVFETTTA GVTIQSPQLD INTVAAGGGS RLFYRNGLFV VGPESAGAHP GPACYRKSGP
     LTVTDANLFL GRLAPDFFPK IFGSGDTQGL DEQASRVLFE GLTKEINQKL IEGGHNREIY
     PDEVAFGFIK VANETMTRPI RSLTEAKGHD TSKHRLATFG GAGGQHAVAI AESLGIRQIL
     IHRYSSVLSA YGMALADVVD ENQEPESKTW ADDDDNKGGV RDALGSRIEE LKKRSTQRLR
     DQGFNNDSIM FEEYLNMRYR GTESDLMILK PSKEEADLHF GGDEWAFGKA FMKQHNQEFG
     FTLPDRDIIV DDVRVRGIGK RFKISEKNVD QQIDESNPKD VTMGQEYRRS LVYFEGGRCE
     TPIYKLDDLK VGERVRGPAI LADDTQTIVV TPGASAFLTK THVVINIGEL DAIQAKISTD
     TVDPILLSVF SHRFMAIAEQ MGRALQKTSV SANVKERLDY SCALFDAEGG LVANAPHLPV
     HLGSMSTCVR RQAWIWQDKL KPGDVIVSNH PEFGGTHLPD ITVLQPAFSQ GKIIFYVASR
     AHHADIGGIL PGSMPPHSKE LYQEGAAIKS EKLVSEGNFD EKRITELLYK EPAQYPSCSG
     TRCLADNLND LKAQIAANKK GANLIRILIE EYGEAVVQFY MHQIQGNAEL SVRNLLKDAS
     KRFAGQELSA IDYMDDGSPI QLKISIDGEN GEAIFDFEGT GPEVHGNINA PEAVTYSAII
     YCLRCLISAD IPLNQGCLKP IDVRIPPGSL LSPSESAAVV GGNVLTSQRV TDVILRCFQA
     CAASQGDTNN LTFGFGGNIP GETETKGFGY YETIAGGSGA GPTWEGASGV HTHMTNTRIT
     DAEVLERRYP VILREFSLRP KSGGNGQHRG GDGVVRDIEF RIPVQVSILS ERRVYHPYGL
     EGGEDAQCGQ NIWVRHVKKK DGSWKNGYIN LGAKNSAQMQ AGERIIIGTP GGGGWGQIGD
     HNRLLQEKDH RDAWWGGSIA KNMATQEASM
//