ID K9H3H5_PEND2 Unreviewed; 1081 AA.
AC K9H3H5;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=ATP dependent RNA helicase (Dob1), putative {ECO:0000313|EMBL:EKV19706.1};
GN ORFNames=PDIG_01530 {ECO:0000313|EMBL:EKV19706.1};
OS Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV19706.1, ECO:0000313|Proteomes:UP000009882};
RN [1] {ECO:0000313|Proteomes:UP000009882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT postharvest pathogen of citrus.";
RL BMC Genomics 13:646-646(2012).
CC -!- SIMILARITY: Belongs to the helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010140}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV19706.1}.
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DR EMBL; AKCT01000010; EKV19706.1; -; Genomic_DNA.
DR AlphaFoldDB; K9H3H5; -.
DR STRING; 1170229.K9H3H5; -.
DR eggNOG; KOG0948; Eukaryota.
DR HOGENOM; CLU_002902_0_1_1; -.
DR InParanoid; K9H3H5; -.
DR OMA; IMLKNYN; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000009882; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18024; DEXHc_Mtr4-like; 1.
DR CDD; cd13154; KOW_Mtr4; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 2.40.30.300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EKV19706.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009882}.
FT DOMAIN 168..324
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 407..608
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..104
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..397
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1081 AA; 122031 MW; 05FA00C34AC7AEB7 CRC64;
MDELFDVFED QPQAVKPSEV APKRLKKNKN KKRQMNGDVK KTADAQPEQK EDVAMTDASA
GEVESADAEA PTTPSEPEQP ETKRPRLDQE PEPVVADSFE TEQEREIAAS GGLSGATDTS
AVVVSHQVRH QVAIPPNYPY VPISQHKPPA NPAKTWPFTL DPFQQVAVSS IQREESVLVS
AHTSAGKTVV AEYAIAQSLK QNQRVIYTSP IKALSNQKYR EFAAEFGDVG LMTGDVTINP
TATCLVMTTE ILRSMLYRGS EIMREVQWVV FDEIHYMRDL NRGVVWEETI ILLPDKVRYV
FLSATIPNAM QFAEWIVKMH NQPCHVVYTN YRPTPLQNYF FPAGGEGIHL VVDEKGVFRE
ENFQKAMSAI ADKKGDDPAD ALAKRKGKGK DKQINKGGNK GPSDIFKIVR MIMLKNYNPV
IVFSFSKREC EAGALQMSKL TFNDDSEKNM VSKVFESAIE MLSPEDRQLP QIQNILPLLQ
QGIGVHHSGL LPILKETIEI LFQEGLIKVL FATETFSIGL NMPAKTVVFT SVRKFDGTSQ
RWVTPSEFIQ MSGRAGRRGL DDRGIVIMMV GEEMDPAVAK EIVRGEQDRL NSAFHLGYNM
ILNLMRVEGI SPEYMLERCF KQFQNTGSVS GLEKELESLE EKRTNMIISD EGTIREYYDL
RKQLDAFADD VQHVITHPNY SLTFIHPGRL IHVKYKDADF GWGVVINQKK RKQASNDTEK
LTPHQSYIVD VLMRTTEGSS IGTKSFQDLP PGVHPAKEGE PARSEVVPIV LSCITEISHI
RIMLPKDITS PSSRNDVMKS VGEVKRRFPD GVPLLDPIEN MQIKDESFKK LLRKIEVLES
RLLSNPLHNS PRLTELYEQY AEKVDLTVKI KAIKKQIAEA MSILQLDELK CRKRVLRRFG
FINEAEVVQL KARVACEIST GDELMLSELL FNGFFNNLTA EQIASVMSCF VFEEKVKEAP
ALAKDELAKP LKDIQSQARI IAKVSQESKM AVNEDEYVQS FHWELMEVIY EWTQGKSFAD
ICKMTDVYEG SLIRVFRRLE ECLRQMAQAA KVMGSEDLES KFEEALGKVR RDIVAAQSLY
L
//
