ID   K9HHX1_9PROT            Unreviewed;       406 AA.
AC   K9HHX1;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Threonine dehydrogenase {ECO:0000313|EMBL:EKV30028.1};
GN   ORFNames=C882_0109 {ECO:0000313|EMBL:EKV30028.1};
OS   Caenispirillum salinarum AK4.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Novispirillaceae; Caenispirillum.
OX   NCBI_TaxID=1238182 {ECO:0000313|EMBL:EKV30028.1, ECO:0000313|Proteomes:UP000009881};
RN   [1] {ECO:0000313|EMBL:EKV30028.1, ECO:0000313|Proteomes:UP000009881}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AK4 {ECO:0000313|EMBL:EKV30028.1,
RC   ECO:0000313|Proteomes:UP000009881};
RX   PubMed=23409257;
RA   Khatri I., Singh A., Korpole S., Pinnaka A.K., Subramanian S.;
RT   "Draft Genome Sequence of an Alphaproteobacterium, Caenispirillum salinarum
RT   AK4(T), Isolated from a Solar Saltern.";
RL   Genome Announc. 1:E00199-12(2013).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKV30028.1}.
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DR   EMBL; ANHY01000010; EKV30028.1; -; Genomic_DNA.
DR   RefSeq; WP_009540769.1; NZ_ANHY01000010.1.
DR   AlphaFoldDB; K9HHX1; -.
DR   STRING; 1238182.C882_0109; -.
DR   PATRIC; fig|1238182.3.peg.2325; -.
DR   eggNOG; COG1063; Bacteria.
DR   OrthoDB; 9773078at2; -.
DR   Proteomes; UP000009881; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd08283; FDH_like_1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009881};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          8..292
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   406 AA;  43344 MW;  0C5135C5024714D0 CRC64;
     MRALCWNGIN DLRVETIDDP IILDPGDVIV KVKLSSVCGS DLHLLDGYVP AMRSGDVLGH
     EFLGEVVETG AGVSKLTKGD RVIVISIIGC GHCWFCDNQL YSLCDNSNAT PGMEETVYGH
     AGAGIFGYSH AFGGYAGSHA EYIRVPYAET NVFKVPDGVS DETAVFVSDA VPTGWMAADL
     ADVQDGDVVA VWGAGGVGLM AMTAARIMGA ERVIAIDRFP DRLKKAHAHA GAEIVNYEKV
     DVHDALMDMT GGRGPDRCID AVGLEAHGTG PGYLYDRAKQ ALRLETGRAT VLRQAVRACR
     KGGTVSVIGV YGGFVDTFPM GALMNKALTM RGGQQHGQRY VPTLFEHIRE GRLDPSYLMT
     HRWPLDRGAE GYGMFKHKTD DCLRVVFDPT LSAGPGANNL GAGGPA
//