ID   K9II17_DESRO            Unreviewed;       269 AA.
AC   K9II17;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Replication factor A protein 2 {ECO:0000256|ARBA:ARBA00043137};
OS   Desmodus rotundus (Vampire bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Phyllostomidae;
OC   Desmodontinae; Desmodus.
OX   NCBI_TaxID=9430 {ECO:0000313|EMBL:JAA46093.1};
RN   [1] {ECO:0000313|EMBL:JAA46093.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Salivary gland {ECO:0000313|EMBL:JAA46093.1};
RA   Francischetti I.M.B., Assumpcao T.C.F., Ma D., Vicente E.C.,
RA   Ribeiro J.M.C.;
RT   "The Vampirome: Transcriptome and Proteome Analysis of the Submandibular
RT   and Accessory Glands of the Vampire Bat and Vector of Human Rabies,
RT   Desmodus rotundus.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the replication factor A protein 2 family.
CC       {ECO:0000256|ARBA:ARBA00007815}.
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DR   EMBL; GABZ01007432; JAA46093.1; -; mRNA.
DR   AlphaFoldDB; K9II17; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd04478; RPA2_DBD_D; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR040260; RFA2-like.
DR   InterPro; IPR014646; Rfa2/RPA32.
DR   InterPro; IPR014892; RPA_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR13989:SF16; REPLICATION PROTEIN A 32 KDA SUBUNIT; 1.
DR   PANTHER; PTHR13989; REPLICATION PROTEIN A-RELATED; 1.
DR   Pfam; PF08784; RPA_C; 1.
DR   PIRSF; PIRSF036949; RPA32; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding {ECO:0000313|EMBL:JAA46093.1}.
FT   DOMAIN          166..261
FT                   /note="Replication protein A C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08784"
FT   REGION          20..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   269 AA;  29117 MW;  0FC474BC99F680EE CRC64;
     MWNSGYESYG SSTFGGAGGY TQSPGGFGSP TPSQAEKKSR ARAQHVVPCT ISQLLSATLV
     DEVFRIGNVE ISQVVIIGII RHAEKAPTNI VYKIDDMTAA PMDVRQWVDT DDASGENTVV
     PPETYVKVAG HLRSFQNKKS LVAFKIMPLD DMNEFTAHIL EVVNAHMMLT RANQPSAGRA
     PISNPGMGEA GNFGGNSFIP ANGLTVAQNQ VLNLIKACPR PEGLNFHDLK NQLQHMTVAS
     IKQAVDFLSN EGHIYSTVDD DHFKSTDAE
//