ID K9IPK7_DESRO Unreviewed; 963 AA.
AC K9IPK7;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Putative transferrin receptor trafficking protein {ECO:0000313|EMBL:JAA49432.1};
OS Desmodus rotundus (Vampire bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Phyllostomidae;
OC Desmodontinae; Desmodus.
OX NCBI_TaxID=9430 {ECO:0000313|EMBL:JAA49432.1};
RN [1] {ECO:0000313|EMBL:JAA49432.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland {ECO:0000313|EMBL:JAA49432.1};
RA Francischetti I.M.B., Assumpcao T.C.F., Ma D., Vicente E.C.,
RA Ribeiro J.M.C.;
RT "The Vampirome: Transcriptome and Proteome Analysis of the Submandibular
RT and Accessory Glands of the Vampire Bat and Vector of Human Rabies,
RT Desmodus rotundus.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GABZ01004093; JAA49432.1; -; mRNA.
DR AlphaFoldDB; K9IPK7; -.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.220.30; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR15603:SF3; SH3 DOMAIN-BINDING PROTEIN 4; 1.
DR PANTHER; PTHR15603; SH3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07653; SH3_2; 2.
DR Pfam; PF00791; ZU5; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 2.
DR PROSITE; PS51145; ZU5; 1.
PE 2: Evidence at transcript level;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Membrane {ECO:0000256|ARBA:ARBA00023176};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000313|EMBL:JAA49432.1};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 55..114
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 317..454
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 654..724
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 963 AA; 106868 MW; 10CF5822861A5B66 CRC64;
MAAQRIRAAN ASGLPRCKSE GTLVDLSEGF SEASFNDVKV PSPSALLGDN PTPFGNAKEV
IAIKDYRPSN FTTLKFSKGD HLYVLDTCGG EWWYAHNTTE MGYIPSSHVR PLNCRNSTLS
DSGVIDLLPD SPDEAAEEFD LLGGWTDDRK GSGKSYSNNP FWTGVQTNPF LNGHVPVGPS
VEEQAPKSTV DLLLFDTGPS SFSDGSSAAV NGTGHGFDEP PATNQLHAQG PVRRDNPFFR
SKRSYSLSEL SVLQAKSDAP ASSGFFTGLK SPVPEQFQSR EDFRAAWLSH RKLARSCHDL
DLLGQSPGWG QTQAVETNIV CKLDSSGGSV QLPDTGISIH VPEGHVAPGE TQQISMKALL
DPPLELNSDR CCSISPVLEV KLSTLEVKTV IVLEMKASAE VKSDIFSKST VGLQCLRSDL
KEGPYVPIPL TYSYGDTVQV HLDNLEPCMY LAIVAHGPNI LYPSTVWDFI NKKVTVGLYG
PKHIHPSFKT VVTIFGHDCA PKTLLVNEVT RQAPSPAPVA LQLWGRHQFV LSRPQDLQVC
MFSNMTNYEV KASEQAKVVR GFQVKLGKVS RLIFPITCQS PGELSDFTLR VQVKDDQQAI
LTQFCVQTPQ PPPKSAIKPS GQRRFLKKNE VGKIILSPFA ATTKYPTFQD RPVSSLKFGK
LLKTVVRQSK NHYLLEYKKG EAIALLSEEK IRLKGQLWTK EWYIGYHQGK VGLVHAKNVL
VVGRARPSLL SGPELSTSVL LEQILRPCKF LTYIYASVRT LLMENISSWR AFADALGYEN
LPLTFFCRAE LDSEPERVAS VLEKLKEDCN NAENKDRKSF QKELMMALLK MDCQGLVVRL
IQDFVLLTTA VEVAQRWREL AEKLAKVSKQ QMDAYESPHR DRNGVVDSEA MWKPAYDFLL
TWSHQIGDSY RDVIQELHTG LDRMRNPVTK RWKHLTGTLI LVNSLDVLRA AAFSPADQDD
FVI
//
