ID K9J663_DESRO Unreviewed; 998 AA.
AC K9J663;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Putative third src logy 3 domain of tyrosine kinase substrate with five sh3 {ECO:0000313|EMBL:JAA52999.1};
DE Flags: Fragment;
OS Desmodus rotundus (Vampire bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Phyllostomidae;
OC Desmodontinae; Desmodus.
OX NCBI_TaxID=9430 {ECO:0000313|EMBL:JAA52999.1};
RN [1] {ECO:0000313|EMBL:JAA52999.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland {ECO:0000313|EMBL:JAA52999.1};
RA Francischetti I.M.B., Assumpcao T.C.F., Ma D., Vicente E.C.,
RA Ribeiro J.M.C.;
RT "The Vampirome: Transcriptome and Proteome Analysis of the Submandibular
RT and Accessory Glands of the Vampire Bat and Vector of Human Rabies,
RT Desmodus rotundus.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GABZ01000526; JAA52999.1; -; mRNA.
DR AlphaFoldDB; K9J663; -.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd12074; SH3_Tks5_1; 1.
DR CDD; cd12077; SH3_Tks5_2; 1.
DR CDD; cd12079; SH3_Tks5_3; 1.
DR CDD; cd12019; SH3_Tks5_4; 1.
DR CDD; cd12020; SH3_Tks5_5; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 5.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035450; SH3PXD2A_SH3_1.
DR InterPro; IPR035452; SH3PXD2A_SH3_2.
DR InterPro; IPR035449; SH3PXD2A_SH3_3.
DR InterPro; IPR035453; SH3PXD2A_SH3_4.
DR InterPro; IPR035454; SH3PXD2A_SH3_5.
DR PANTHER; PTHR15706:SF2; BUD EMERGENCE PROTEIN 1; 1.
DR PANTHER; PTHR15706; SH3 MULTIPLE DOMAIN; 1.
DR Pfam; PF00018; SH3_1; 3.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00326; SH3; 5.
DR SUPFAM; SSF50044; SH3-domain; 5.
DR PROSITE; PS50002; SH3; 5.
PE 2: Evidence at transcript level;
KW Kinase {ECO:0000313|EMBL:JAA52999.1};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transferase {ECO:0000313|EMBL:JAA52999.1}.
FT DOMAIN 35..94
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 135..194
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 317..376
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 706..765
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 937..998
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 284..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 807..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..924
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..541
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..790
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAA52999.1"
SQ SEQUENCE 998 AA; 108896 MW; 10E9C6E1D6475529 CRC64;
RPMDRGRPGR GAMAGRWLTA CFLPSPGADT SAEPMILEQY VVVSNYKKQE NSELSLQAGE
VVDVIEKNES GWWFVSTSEE QGWVPATYLE AQNGTRDDSD INTSKSGEVS KRRKAHLRRL
DRRWTLGGMV NRQHSREEKY VTVQPYTSQS KDEIGFEKGV TVEVIRKNLE GWWYIRYLGK
EGWAPASYLK KAKEDLPARK KNLAGPVEII GNIMEISNLL NKKASGDKET PPAEGEGPEA
PIAKKEISLP ILCNASNGSA LAVPERTVSK LAQSSPAVAR IAPQRAQISS PNLRTRPPPR
RESSLGFQLP KPPEPPSVEV EYYTIAEFQS CISDGISFRG GQKAEVIDKN SGGWWYVQIG
EKEGWAPASY IDKRKKPNLS RRTSTLTRPK VPPPAPPSKP KEAEEGPAGT GESQDSPLKL
KYEEPEYDIP AFGFDSEPEL SEEPVEDKGS GDKRPTQPYR PSPASSLQRA RFKVGGSSED
VAPEEETIYE NEGFRPCAED TLSAGRSSRD SDSPGGSPLS LARKNSPKSD SPKSSSLLKL
KAEKNAQAEL GKNHSSASFS SSITINTTCS SSSSSSSLSK HSSDLKPRSA SDAGIRGTPK
VGVKKDADLK AGLTCARAKP SVRPKPFLNR AESQSQEKMD ISTLRRQLRP TGQLRGGLKG
SKSEDSELPP QTASEGPNEG SRRGSADIIT LPAATSPGPT KKGQEGQTTS YMTRSAYQKV
QDSEISFPAG VEVQVLEKLE SGWWYVRFGE LEGWAPSHYL VLGENEPLDP TGKEPDTVTA
KGKQEGKSDS LEKIEKRVQA LNTVNQSKRA TPPIPSKPPG GFSKTSGTGV VKMRNGVRQV
AVRPQSVFVS PPPKDNNLSC ALRRNESLTA TDGLRGVRRN SSFSTARSAA AEAKGRLPER
AASQGSDTPL LPTQRNGIPV SPVRPKPIEK SQFIHNNLKD VYVSIADYEG DEETAGFQEG
VSMEVLERNP NGWWYCQILD GARPFKGWVP SNYLEKKN
//
