ID K9RWD2_SYNP3 Unreviewed; 1374 AA.
AC K9RWD2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:AFY61594.1};
GN OrderedLocusNames=Syn6312_2494 {ECO:0000313|EMBL:AFY61594.1};
OS Synechococcus sp. (strain ATCC 27167 / PCC 6312).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=195253 {ECO:0000313|EMBL:AFY61594.1, ECO:0000313|Proteomes:UP000010379};
RN [1] {ECO:0000313|Proteomes:UP000010379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27167 / PCC 6312 {ECO:0000313|Proteomes:UP000010379};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
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DR EMBL; CP003558; AFY61594.1; -; Genomic_DNA.
DR RefSeq; WP_015125137.1; NC_019680.1.
DR STRING; 195253.Syn6312_2494; -.
DR KEGG; syne:Syn6312_2494; -.
DR PATRIC; fig|195253.3.peg.2547; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG5000; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_256055_0_0_3; -.
DR OrthoDB; 9763461at2; -.
DR Proteomes; UP000010379; Chromosome.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 5.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 6.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR016132; Phyto_chromo_attachment.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 5.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 5.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 6.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 6.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 4.
DR PROSITE; PS50046; PHYTOCHROME_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010379}.
FT DOMAIN 5..67
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 80..132
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 225..277
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 278..348
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 395..446
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 512..582
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 648..784
FT /note="Phytochrome chromophore attachment site"
FT /evidence="ECO:0000259|PROSITE:PS50046"
FT DOMAIN 881..933
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 966..1099
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 1128..1374
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1374 AA; 157488 MW; DB198B8B131AF36E CRC64;
MFNDLIADFA QLIALHTDDL ICVHEPDGSY LYLTPSCQDL LGYDPAELVG STPYFLFHPD
DVEAIRSGPH ALALQGVTNV HITYRMRKKS GGYIWLETLT RPILDEAGNV LLIVTTSRDI
TQRRLVEKQL STNEQLLETF FSQSLDACFI KLLPRPLNWQ DEPNREAAIE YALFNLRITK
VNDATCTMYR AGRERLLGLC FGDMFRKDLD QGRQLLKALF HLGRFQTELH LQRLDNTWMW
VDCNFVCLYD ERGWIRGCFD VKKDITERKE TRIKLEEAYA AVTNVLESTT DGFFSVDQDW
SITYVNHNFE QTLKTKRQNI LGKNFWELFP DARGTLFESE YSRAFRENLP VQFEEFYPGT
QHWYAVRAYP TEQGLSIYFQ NVTEQKLAEL QLAETNNRLT TVLESTTDGF FNLNSDWLIT
YCNSKFEETV GLGKEQLIGH NLWELFSDAV GTPFELKFKQ ALVEQVPIEV EEFYPGLGRW
FYVKAYPVDS GLAVYFQDVT NRRIAEAKLA EVNQELSSVL ESTTDAFISV DQQGMLTYIN
RNFERRTGLT RAQLLGHTPW EVFPDLEHTA FFQAIEQAQG NHQPQKVEYF CPYTQTWFLA
NIYPTPGGFS IYLQDVTAQK KREAERQRQS DLTELLLRLS IQVRESLEVP KILQTTVDEV
RQFLDVNRVI VYQFLPDWSG KIVAEAVDNP DYALLNQIIY DPCFGASQVG PYRLGRISQV
MNIHDSDMNP CYVEFLAQFQ VQANLVVPII YQDQLLGLLI AQHCQQPRAW QEDEVNLLKQ
LATQVGIAVS RAKLVTALKE QEARYRAIVE DQTELIYRCS SDGILTFANA AFCRYLHLIE
PGEIKADQCY FDQAVRHPFN EVETARFAQQ LAALTPAHPV SSIECAVDLP SGDQAWYEWT
MRALYDSANQ LREYQCLGRE ITRRKKVEFQ LIHDALYDSL TGLPNRVLLL ERLNQAWNRY
RRHPDCPFVL LFIDVDRFKR INDSLGHQAG DQILMTLAER LQVVLRATDT LARLSGDEFV
LLAEDINPGI DLDHLIGRLQ QTAEQPITIY DNLIKLTLSI GVAWSSEAYS QPDELLRDAD
IAMYQAKRRG RHQCLTFTPE MHLEARFTLS LESELRSAIL TAQTRDPLLL TESELAKELT
ATPLQIYYQP IVDLSSRHVI GLEALCRWFH PRRGVISPSE FIPLAEETGL ILPLGQWVLK
TAVAHFSQWY QTLGPGNIPK LSVNLAPQQF LQSNLVNDVA DILETYDLPP KYLHLEITET
AMMTSLDVVV RVARQLQDLG VFLNIDDFGT GYSSLSRLHQ LPIQALKIDR SFVLRLDPDI
YPLWDFEAPI PSQASGDIIQ AMLSLGQSLE MDVIAELPAK GALTVYQFRR TACC
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