ID K9VZE5_9CYAN Unreviewed; 2040 AA.
AC K9VZE5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Cri9333_1993 {ECO:0000313|EMBL:AFZ12872.1};
OS Crinalium epipsammum PCC 9333.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Gomontiellaceae;
OC Crinalium.
OX NCBI_TaxID=1173022 {ECO:0000313|EMBL:AFZ12872.1, ECO:0000313|Proteomes:UP000010472};
RN [1] {ECO:0000313|EMBL:AFZ12872.1, ECO:0000313|Proteomes:UP000010472}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 9333 {ECO:0000313|EMBL:AFZ12872.1,
RC ECO:0000313|Proteomes:UP000010472};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Crinalium epipsammum PCC 9333.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP003620; AFZ12872.1; -; Genomic_DNA.
DR RefSeq; WP_015202988.1; NC_019753.1.
DR STRING; 1173022.Cri9333_1993; -.
DR KEGG; cep:Cri9333_1993; -.
DR PATRIC; fig|1173022.3.peg.2153; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG0784; Bacteria.
DR eggNOG; COG2198; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR HOGENOM; CLU_000445_34_2_3; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000010472; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF01627; Hpt; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00073; HPT; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50894; HPT; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:AFZ12872.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000010472};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..269
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1520..1746
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1772..1889
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1944..2040
FT /note="HPt"
FT /evidence="ECO:0000259|PROSITE:PS50894"
FT MOD_RES 1821
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 1983
FT /note="Phosphohistidine"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
SQ SEQUENCE 2040 AA; 229472 MW; E13EF715D250FE14 CRC64;
MINIPGYQIK GQIYESQKKL IYQGKSDIDH KPVIIKVLKP GFFTAEEIAR LKQEYIISHD
LNYLGIVKTY SIENYQNGFA LILEDFGGKS LRQVFTAKPM QLPEFLRIAI VLAETLIELH
KIPIIHKDIK PANIIINPQT SEVKITDFSI ASRLGVENQV VSNPNLLEGT LAYMSPEQTG
RMNRSVDYRT DFYSLGVTFY EMLTGELPFI HSDPMELVHS HIAKQPTTPA AIADIPQVIS
DIVMKLLAKN AEDRYQSAAG LKFDLENCLQ QLQSKGKIDD FAVGKRDRSN QLLIPQKLYG
RENEVQTLMD AFDLVSNGAS ELILVSGYSG IGKTSIVAEV HKPIVKARGY FISGKFDQFK
RNIPYSALIQ AFQELISQVL TENAEQITVW RDKLLNALGE QGRVITEVIP KVELIIGQQP
ELTPIGAFEA QNRFNRVFQQ FIQVFCQPNH PLVVFLDDLQ WADSASLKLI QLLVTNFDSK
YLLMINAYRD NEVSSTHSFI QTLEKIKDTE ATINQIVVQP LSLYCVNQII AETLKTDPEA
EQLKPLVSIV YNKTQGNPFY LTQLLKSLYS ENFLVYQVDN DTWHWDIQKI QAVGITDFNV
VELLARSLRK LPPETQNILK LAACIGNQFN LDVLALVNQE SDTVTANHLW SALQCGLILP
TSTAYKIPLV FQEEEAKYFH ANDVKVEYKF LHDRVQQSAY SLIPEAERKA THLKIGQQLL
RNTTPESQNE NIFAIVNHLN FGIDLLNNQL DKNELAELNL IAGQKAKSAM AYEAAVNYLN
LALNLLCPES WQEQYYLAFT IYKEAAEAEY LNASLDQAET LCNFALTQTQ VILDQIKFYL
IKFKIHLAKN QINLALDLGL TILKMLGVPL SETPPSDINI EKLANLPRMT DPYKLAAMEI
LMLLYSPATI SQSPLTLPFI YTMLALSSEY GNSPPSIYAY AIYGVITVWL IPDINLAYKL
SQLSIQVLEK LNAKELYAKV YFTKEINISY KKEHLRETIK PLHECISNGL EVGDVEFSCN
AANYYCNHLF FKGEVLDVVA QKQSEYIKYI QKLGQKHLLT ILKVFAQAVA NLLNSPRNPC
LLTGEFMNET ETLPFFIGSN NLISIFNAYY FKCWLNFLFK EYKEAVKYGE LILTKCGAVK
AEVIVVTQHN FYYSLALLSE YYRLKIKTNS SNQVDLEKYL EQVRKNQEKM KYWAEHCPEN
FQHKYDLVEA EKAKVLGEKE KTIPSVSYAS ALYEQAIKGA KLQGYIQEEA LALELAGEFH
LSCEHDRLGK YYLLEAYYCY VKWGAIAKAK HLEIQYPDLI PPSEKITKSK SFNTTLSSSS
SADILDLTTV IKASQTIAGE IVLDKLLEKL MKIIIENAGA QTGFFILKNE FQAFIEARLV
SEENQVIVRQ SPLSENTKLL PLSVINFVER TKEDVILINA SSSTQFNNDA YITENQPLSV
LCTPIIHQNQ LLGILYLENN LITGVFTTER VGLLKILSAQ AAISLQNALL YRVAEQKAIL
EKAKVAAEAA NQAKSEFLAM ISHEIRTPMN AIVGMSQLLL NTTLQPQQKA FVNTISTSSE
SLLTILNDIL DLSKIESGKL ELEQQSFNLY RCIEESLALL TPKVIEKGLK LTYSIDPPTP
ENLHGDSTRL RQVLLNLLSN AIKFTQTGGI NLAVTAEKLA RETNNESVYE IQFAIKDTGI
GIPLDRIQQL FNPFTQVDAS ISRRYGGTGL GLAICKKLVE MMGGKISVES ELGHGSTFYF
TIIATAASQE FALSTEESNG KIPHLAQEVP LKILLAEDNK VNQQVALLTF EALGYQIQIV
NHGLEALQEL QQQNYDVVFM DIQMPEMDGI TATSYINQEW SSESRPQIIA MTAYVNKEDK
ERCFQAGMDG YISKPIRIDE LVKVLKQCYL SINKNVAGCQ RLTSRQELEV SPSSSLLQQS
QDTTLEVIDR YILQSLRQMA GANADEFLTK IINNYFEVAP QLLSEIDAAI DTADANKLFQ
AAHALRSSSA NLGAAKLSGI CQELEAIGRS GTTVGAQSLR SQLKSMYQLV KDALLRECKD
//
