ID K9Y6H6_HALP7 Unreviewed; 532 AA.
AC K9Y6H6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:AFZ42521.1};
GN OrderedLocusNames=PCC7418_0285 {ECO:0000313|EMBL:AFZ42521.1};
OS Halothece sp. (strain PCC 7418) (Synechococcus sp. (strain PCC 7418)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Halothecacae; Halothece cluster; Halothece.
OX NCBI_TaxID=65093 {ECO:0000313|EMBL:AFZ42521.1, ECO:0000313|Proteomes:UP000010481};
RN [1] {ECO:0000313|Proteomes:UP000010481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7418 {ECO:0000313|Proteomes:UP000010481};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP003945; AFZ42521.1; -; Genomic_DNA.
DR RefSeq; WP_015224399.1; NC_019779.1.
DR AlphaFoldDB; K9Y6H6; -.
DR STRING; 65093.PCC7418_0285; -.
DR KEGG; hao:PCC7418_0285; -.
DR PATRIC; fig|65093.3.peg.298; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_021572_5_0_3; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000010481; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR025274; DUF4070.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034530; HpnP-like.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF3; HYPOTHETICAL METHYLTRANSFERASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13282; DUF4070; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDF00303; hopanoid_C2-methyltransferase; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010481}.
FT DOMAIN 163..393
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 532 AA; 61420 MW; A1F2700F2B89EA7E CRC64;
MKALLLYPLF PKTFWSYDRF MDIVNMKATI PPLGIITVAS LLPQDWDIRF YDRNVTLETE
ADWDWCDLIM VSAMIAQRED FHDLIRKAVQ KGKKVAVGGP YPTSVPEDAM ESGADYLILD
EGEITIPPFV DAITRGEEQG IFRANEKPDV TQSPLPRFDL LQREDYVMMA VQFSRGCPFH
CEFCDIISLY GRKPRTKEID QTLAELQTLY DLGWRRSVFI VDDNFIGNQR NVKRLLRALI
PWIQERNYPF TFLTEASVNL AEDPELLELM KQAGFYGVFL GIETPDQDSL TVTRKHQNTR
SPLAEACHQI NQAGLMIYAG FIIGFDGERS GAGERIQAFV EETSIPQPML GLLQAPQNTA
LWERLKTEQR LLEDIGWTKF GEQNTLMNFI PTRPLSEIAQ EYMQALWTMY EPAAYLQRCF
QHCLKITPNP HFRQRISFPM TTAVRLITQV IWKQGVQMKA IRKQFWHQFW MLLKTKPQLL
SLYLGLCAAG EHFWEYRVLT RERITQQLGY DPLVTSPALL SKSKSVENCI TS
//
