ID K9ZH93_ANACC Unreviewed; 453 AA.
AC K9ZH93;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Beta-ketoacyl-acyl-carrier-protein synthase I {ECO:0000313|EMBL:AFZ58561.1};
DE EC=2.3.1.41 {ECO:0000313|EMBL:AFZ58561.1};
GN OrderedLocusNames=Anacy_3151 {ECO:0000313|EMBL:AFZ58561.1};
OS Anabaena cylindrica (strain ATCC 27899 / PCC 7122).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Anabaena.
OX NCBI_TaxID=272123 {ECO:0000313|EMBL:AFZ58561.1, ECO:0000313|Proteomes:UP000010474};
RN [1] {ECO:0000313|Proteomes:UP000010474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27899 / PCC 7122 {ECO:0000313|Proteomes:UP000010474};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|RuleBase:RU003694}.
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DR EMBL; CP003659; AFZ58561.1; -; Genomic_DNA.
DR RefSeq; WP_015215187.1; NZ_AP018166.1.
DR AlphaFoldDB; K9ZH93; -.
DR STRING; 272123.Anacy_3151; -.
DR KEGG; acy:Anacy_3151; -.
DR PATRIC; fig|272123.3.peg.3435; -.
DR eggNOG; COG3321; Bacteria.
DR HOGENOM; CLU_000022_16_2_3; -.
DR OrthoDB; 499075at2; -.
DR Proteomes; UP000010474; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43074; OMEGA-3 POLYUNSATURATED FATTY ACID SYNTHASE PFAB-RELATED; 1.
DR PANTHER; PTHR43074:SF1; PKS_AT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:AFZ58561.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010474};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:AFZ58561.1}.
FT DOMAIN 1..448
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 453 AA; 48438 MW; 27BA01364803C363 CRC64;
MEKIAIIGLS CLFPDAKNPE EFWQNLTEEK DSTSPLSVAD LGIDPAIFYD SEKGKPEKFY
FLKGGFIRDF KFDASDYNLP GVFVESLDNT FKWSLYAAKQ AIIQSGYWGN KTALSKCGVI
LGTLSLPTKA SNQLFAPLYQ QTIEPAIGEL LQEKDFRLGG ALTAAKASPY NAMVSGLPAA
IISRAFSLSG THCCIDAACS SAFYAIKLAS HYLQSGKADL MLAGAISCSD PLFLRMLFSG
IQGYPENGIS RPLDKASRGL ITSEGIGMVM LKRYSDAVRD GDRILATICG NGLSNDGKGK
HLLSPNAQGQ TLAYQRAYAE ANLNPQTIDY LECHATGTLL GDTTECNSVE GFFGQHQATP
LVGSAKTNVG HLLVAAGMVG ITKTILSMSH GVIPATIDIS EPMGSEHNVI SPQNIVRTAT
PWPSKGTKHV ALSAFGFGGT NSHLILEQGE VSK
//
