ID K9ZHG3_ANACC Unreviewed; 446 AA.
AC K9ZHG3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Peptidase U62 modulator of DNA gyrase {ECO:0000313|EMBL:AFZ58631.1};
GN OrderedLocusNames=Anacy_3223 {ECO:0000313|EMBL:AFZ58631.1};
OS Anabaena cylindrica (strain ATCC 27899 / PCC 7122).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Anabaena.
OX NCBI_TaxID=272123 {ECO:0000313|EMBL:AFZ58631.1, ECO:0000313|Proteomes:UP000010474};
RN [1] {ECO:0000313|Proteomes:UP000010474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27899 / PCC 7122 {ECO:0000313|Proteomes:UP000010474};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP003659; AFZ58631.1; -; Genomic_DNA.
DR RefSeq; WP_015215257.1; NZ_AP018166.1.
DR AlphaFoldDB; K9ZHG3; -.
DR STRING; 272123.Anacy_3223; -.
DR KEGG; acy:Anacy_3223; -.
DR PATRIC; fig|272123.3.peg.3514; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_4_0_3; -.
DR OrthoDB; 9803618at2; -.
DR Proteomes; UP000010474; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR047657; PmbA.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000010474}.
FT DOMAIN 24..87
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 117..220
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 227..445
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 446 AA; 48450 MW; 89507B89B95FF6D6 CRC64;
MTKIQEIATY AQENAAKLGI KKFDIYGSTV DDTSVQVDQG EPKQVKASNR SGVIVRVWNE
ENTMGVTSTT DVDPLGLELA LKTAYEASFF GVKENIPDFS PEATVPIANP RHEKAPQSPV
SELIEKLLVA EKELLSTHPA ITSVPYNGLA QRDSDRFYVN SDGAVRTESH SLATVYLYTK
TEEENKKPRS AGAYRVKESL AELDIAGCIK ETAEKTISHL NYEKIKTGKY RVVFSPEAFL
SLLGAFSNLF NAQSILDNQS LSKAEDIGKQ LASPLLSVYD DALHPANIGA ETFDGEGTPT
RQVKLIENGV LTSFLHSAGT AKRFNTTPTG NASIGAKVSV SPNFYHVFAA DKPEQELSLE
TAENVILIDD LQALHAGVKS LQGSFSLPFD GWLINKGEKT SIESATVAGD FLEVLQSIVY
VEKEVELTPG GVCPRVWVSE LSITGE
//
