ID   K9ZNX2_ANACC            Unreviewed;      1502 AA.
AC   K9ZNX2;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Na-Ca exchanger/integrin-beta4 {ECO:0000313|EMBL:AFZ60494.1};
GN   OrderedLocusNames=Anacy_5162 {ECO:0000313|EMBL:AFZ60494.1};
OS   Anabaena cylindrica (strain ATCC 27899 / PCC 7122).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Anabaena.
OX   NCBI_TaxID=272123 {ECO:0000313|EMBL:AFZ60494.1, ECO:0000313|Proteomes:UP000010474};
RN   [1] {ECO:0000313|Proteomes:UP000010474}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27899 / PCC 7122 {ECO:0000313|Proteomes:UP000010474};
RX   PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA   Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA   Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA   Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA   Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT   "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT   genome sequencing.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR   EMBL; CP003659; AFZ60494.1; -; Genomic_DNA.
DR   RefSeq; WP_015217109.1; NZ_AP018166.1.
DR   STRING; 272123.Anacy_5162; -.
DR   KEGG; acy:Anacy_5162; -.
DR   PATRIC; fig|272123.3.peg.5604; -.
DR   eggNOG; COG0739; Bacteria.
DR   eggNOG; COG2931; Bacteria.
DR   HOGENOM; CLU_005721_1_0_3; -.
DR   OrthoDB; 490661at2; -.
DR   Proteomes; UP000010474; Chromosome.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   Gene3D; 2.60.40.2030; -; 3.
DR   Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 5.
DR   InterPro; IPR038081; CalX-like_sf.
DR   InterPro; IPR003644; Calx_beta.
DR   InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR   InterPro; IPR001343; Hemolysn_Ca-bd.
DR   InterPro; IPR013858; Peptidase_M10B_C.
DR   InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR   PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR   PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR   Pfam; PF03160; Calx-beta; 3.
DR   Pfam; PF00353; HemolysinCabind; 10.
DR   Pfam; PF08548; Peptidase_M10_C; 4.
DR   PRINTS; PR00313; CABNDNGRPT.
DR   SMART; SM00237; Calx_beta; 3.
DR   SUPFAM; SSF51120; beta-Roll; 6.
DR   SUPFAM; SSF141072; CalX-like; 3.
DR   PROSITE; PS00330; HEMOLYSIN_CALCIUM; 6.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010474};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          873..972
FT                   /note="Calx-beta"
FT                   /evidence="ECO:0000259|SMART:SM00237"
FT   DOMAIN          985..1088
FT                   /note="Calx-beta"
FT                   /evidence="ECO:0000259|SMART:SM00237"
FT   DOMAIN          1103..1204
FT                   /note="Calx-beta"
FT                   /evidence="ECO:0000259|SMART:SM00237"
FT   REGION          196..216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1502 AA;  156846 MW;  D932ABEFC5F7FD1D CRC64;
     MWKIHTSPIL MNPLLSSTLT LTHNQLSAFS SLDSFWQVFD TAFGTQYNRR IAEILRLQWQ
     AGDFSQIPQI EILDSSILGN ANGAYASSTN KIYLSDTFVA TATPAAISAL LLEEIGHFVD
     SQINLTDSAG DEGAIFAELV QGYSLDDATL QALQAEDDSA TITVNGQTIQ VEQQNFTGTS
     GSDNITGTSD DDVIQGLGGN DTLSGQGGND QLFGGTGSDT LTGGTGQDQF VFEYFNGSSI
     AQDLDVVTDF VQGEDKIDLR NVGIADYQTL SYLISDDSLS NAVIAARYNN SSSSIYGYRL
     RINGFSSSQL AATDFIFSTS VVNDTITGTN NSDDLFGGLG NDILQGSGGN DRLFGEQGDD
     RFLGGTGSDN FYGGTGLDTF VFEYFNGSSI AQDLDIVSDF VQGQDKIDLR TVGIADYQTL
     LTLISDDSLG NAVIAARYNN SSNPIYGYKL KINGFSNSQL AATDFIFSTL VVNDNFTGTN
     NSDDLFGGLG NDTLQGSGGD DRLFGEQGDD RFLGGTGSDT LTGGTGLDQF IFEYFNGSTL
     SQDLDVVTDF VQGEDKIDLR TVGIADYQTL LTLISDDSLG NAVIAARYNN SSNPIYGYKL
     KINGFSSSQL AATDFIFSTL VVNDTITGTN NSDDLFGGLG NDNLQGSGGD DRLFGEQGDD
     RFLGGTGSDT FYGGTGQDQF VFEYFTGFTN SQDLDVVTDF VKGQDKIDLR NIGIADYQTL
     LTLISDDVLG NALITTRKNN STGDYRMQID GFSSSQLAAT DYILSTSVVN DTITGTNNRD
     DLFGGLGNDT LQGQNGNDRL FGEQGDDRLF GGIGNDSLYG GEGSDTAVYS GTRSQYQITS
     NAGVFTITDS VANRDGIDTL YGVEKVQFSD QIITIGDVAL PSITLAVSPA SVTEDGAANL
     VYTFTRTGST TNALTVNYSI GGTAANTDYT GATRGTGKTI TFAAGSSTAT LIIDPTADTT
     VEANETVALT LATGTGYTIG TTAAVTGTIT NDDVALPSIT LAVSPASVTE DGTANLIYTF
     TRSGGTTNAL VVNYSIGGTA SSNDYTGATP GTGKTITFAA GSSTTTLIID PTADTTVEAN
     ETVALTLATG TGYTIGTTAA VSGTITNDDE TSFITVNLSA DQTIVEGQTN PQNVTYTVTL
     SDTSTQTITV NYATANGTAI AGSDYTSTTG TLTFNPGVTT QSIIIPIVND AINEPNETFT
     VTLSSPTNAS LGTKASAITT ITDTLNASTT TTLAAGIENL TLIGTTAING KGNVNDNVLR
     GNSANNILTG LNGNDTYAFV ANSALGTDRV VETATGGIDT LDFTDTTAAV KVNLGTTTTQ
     TVNSNLKLVL SVNNVIENTT GGNGNDRLTG NSLNNLLVGG DGNDQLQGLA GNDTLSGGHG
     DDVLTGGVGA DEYRFQGNGV FNTNLGVDLI TDFAVGQDKI ALSKATFTAI TNAVGQALTD
     FAVVANDGLV DPSTARIVYS QETGSIFYNQ NGNVLNATAV FEFAYLSNPD ITLSSSDFIL
     IA
//