ID L0A3Y2_DEIPD Unreviewed; 854 AA.
AC L0A3Y2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=DNA mismatch repair protein MutS {ECO:0000313|EMBL:AFZ68561.1};
GN OrderedLocusNames=Deipe_3115 {ECO:0000313|EMBL:AFZ68561.1};
OS Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 /
OS KR-200).
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=937777 {ECO:0000313|EMBL:AFZ68561.1, ECO:0000313|Proteomes:UP000010467};
RN [1] {ECO:0000313|Proteomes:UP000010467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19664 / LMG 22246 / CIP 109416 / KR-200
RC {ECO:0000313|Proteomes:UP000010467};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Lu M.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Pukall R., Steenblock K., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome of Deinococcus peraridilitoris DSM
RT 19664.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC {ECO:0000256|RuleBase:RU003756}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
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DR EMBL; CP003382; AFZ68561.1; -; Genomic_DNA.
DR RefSeq; WP_015236859.1; NC_019793.1.
DR AlphaFoldDB; L0A3Y2; -.
DR STRING; 937777.Deipe_3115; -.
DR KEGG; dpd:Deipe_3115; -.
DR PATRIC; fig|937777.3.peg.3127; -.
DR eggNOG; COG0249; Bacteria.
DR HOGENOM; CLU_002472_4_0_0; -.
DR Proteomes; UP000010467; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756};
KW Reference proteome {ECO:0000313|Proteomes:UP000010467}.
FT DOMAIN 692..708
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 854 AA; 92685 MW; C9824F063418C43A CRC64;
MPLNVPQSVL KGNGPGVLPP MLEQYVHLRD QHPDYLVLFQ VGDFFETFGE DAERLSRLLG
ITLTHKTSKD FSTPMAGIPV RAKDQHIERL LAAGVRVAVA EQMELPLSGL VERRVTELLT
PGTLTDERLL SAEENYLAAV ASGDGYALAL LDLSTGEFRC AAFGTRGALY DELARYRARE
VLLAPEFEEN AALMADFRQR FPLMVSRGSF EEDAAREELQ HTLGSVPESL VTSALVRACG
AALAYARATQ QGRLEMVTRL IRYEPGASLH LPESAIRALE LFEPNAHGGQ TLIACLAHTR
TAGGRRRLRA WLRSPLLDEL SIRSRLDAVD ALVQASDLRG GVRSVLYRAH DLERLAARVS
SRRAMPKEVV SLARTLELLP ELEVLLAGHD GVLGHLGARL SALPEVVMLI RAALVDNPPL
RLGEGGLIRE GFHAELDALR AEALAGREWM AELEARERAR TGLPVKVGFN NVAGYYLEVT
QAHAHKVPAD YRQIATLKDR ARFTRADVRE REREIARCET AAERLEVEAF TELRDTLAQH
TEALSEVAGA LSELDVLSTL ADIAFARGWS RPRTLGAGAT ELRLRQARHP VVELALSDSF
VPNDADLDTT RRVLLLTGPN MAGKSTYLRT VALCALLHQI GSFVPADAAE LPLFDGIHTR
IGASDDLAGG RSTFMVEMSE LAAILHGATS RSLVILDEVG RGTSTLDGLA IAWATLEHLH
RTGAFALFAT HYFELTRLEG ELPGVVNLHV AAQEEAGALT FYHQVVPGAA KSSYGVEVAR
LAGLPGAVTA RAGQLLTGLA ARDGGDSGVV QELAALDLAR LTPLQALELL HAWQRRLAEG
NMGENLSQDA RAAS
//
