ID L0E1I7_THIND Unreviewed; 292 AA.
AC L0E1I7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Octaprenyl-diphosphate synthase / Dimethylallyltransferase / Geranyltranstransferase (Farnesyldiphosphate synthase) / Geranylgeranyl pyrophosphate synthetase {ECO:0000313|EMBL:AGA35070.1};
DE EC=2.5.1.1 {ECO:0000313|EMBL:AGA35070.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:AGA35070.1};
DE EC=2.5.1.29 {ECO:0000313|EMBL:AGA35070.1};
GN Name=ispA [H] {ECO:0000313|EMBL:AGA35070.1};
GN OrderedLocusNames=TVNIR_3434 {ECO:0000313|EMBL:AGA35070.1};
OS Thioalkalivibrio nitratireducens (strain DSM 14787 / UNIQEM 213 / ALEN2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Thioalkalivibrio.
OX NCBI_TaxID=1255043 {ECO:0000313|EMBL:AGA35070.1, ECO:0000313|Proteomes:UP000010809};
RN [1] {ECO:0000313|Proteomes:UP000010809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14787 / UNIQEM 213 / ALEN2
RC {ECO:0000313|Proteomes:UP000010809};
RA Tikhonova T.V., Pavlov A.R., Beletsky A.V., Mardanov A.V., Sorokin D.Y.,
RA Ravin N.V., Popov V.O.;
RT "Complete sequence of Thioalkalivibrio nitratireducens.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003989; AGA35070.1; -; Genomic_DNA.
DR RefSeq; WP_015260169.1; NC_019902.2.
DR AlphaFoldDB; L0E1I7; -.
DR STRING; 1255043.TVNIR_3434; -.
DR KEGG; tni:TVNIR_3434; -.
DR PATRIC; fig|1255043.3.peg.3465; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_0_0_6; -.
DR OrthoDB; 9805316at2; -.
DR Proteomes; UP000010809; Chromosome.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004311; F:farnesyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:AGA35070.1}.
SQ SEQUENCE 292 AA; 31257 MW; 8156940D39235C7A CRC64;
MNSQIEAYQK RIEAFLDRML DSAEAPVPEL IAAMRYSTLG GGKRLRPLLV YATGRAVAAP
EASLDPIAAA VEMIHVYSLI HDDLPAMDDD DLRRGKPTCH KVYGEATAIL AGDALQALAF
ATLLDAGDGL DTDTRLVLAR DLAHASGIRG MAGGQAIDLA SEGRSLDITD LETMHRLKTG
ALIRASVLLP AQAGHADAST QARLGIYADC IGLAFQIRDD VLDVEGDPEL LGKACGADSL
LEKATFPSLL GLETSRHRAT ELVDEALASL QPFGTEADLL RFLARYIVER MH
//
