ID L0EUQ9_LIBCB Unreviewed; 1085 AA.
AC L0EUQ9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=type I site-specific deoxyribonuclease {ECO:0000256|ARBA:ARBA00012654};
DE EC=3.1.21.3 {ECO:0000256|ARBA:ARBA00012654};
GN OrderedLocusNames=B488_07050 {ECO:0000313|EMBL:AGA64697.1};
OS Liberibacter crescens (strain BT-1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Liberibacter.
OX NCBI_TaxID=1215343 {ECO:0000313|EMBL:AGA64697.1, ECO:0000313|Proteomes:UP000010799};
RN [1] {ECO:0000313|EMBL:AGA64697.1, ECO:0000313|Proteomes:UP000010799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BT-1 {ECO:0000313|EMBL:AGA64697.1,
RC ECO:0000313|Proteomes:UP000010799};
RX PubMed=23408754; DOI=10.4056/sigs.3326772;
RA Leonard M.T., Fagen J.R., Davis-Richardson A.G., Davis M.J., Triplett E.W.;
RT "Complete genome sequence of Liberibacter crescens BT-1.";
RL Stand. Genomic Sci. 7:271-283(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage of DNA to give random double-stranded
CC fragments with terminal 5'-phosphates, ATP is simultaneously
CC hydrolyzed.; EC=3.1.21.3; Evidence={ECO:0000256|ARBA:ARBA00000851};
CC -!- SIMILARITY: Belongs to the HsdR family.
CC {ECO:0000256|ARBA:ARBA00008598}.
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DR EMBL; CP003789; AGA64697.1; -; Genomic_DNA.
DR RefSeq; WP_015273124.1; NC_019907.1.
DR AlphaFoldDB; L0EUQ9; -.
DR STRING; 1215343.B488_07050; -.
DR REBASE; 58213; LcrBT1ORF7030P.
DR KEGG; lcc:B488_07050; -.
DR PATRIC; fig|1215343.11.peg.726; -.
DR eggNOG; COG0610; Bacteria.
DR HOGENOM; CLU_010804_0_0_5; -.
DR Proteomes; UP000010799; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1570.50; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR007409; Restrct_endonuc_type1_HsdR_N.
DR InterPro; IPR040980; SWI2_SNF2.
DR PANTHER; PTHR42927; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42927:SF1; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04313; HSDR_N; 1.
DR Pfam; PF18766; SWI2_SNF2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AGA64697.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010799};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT DOMAIN 292..527
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|SMART:SM00487"
SQ SEQUENCE 1085 AA; 121690 MW; 2F42A4D5D326CB82 CRC64;
MRASAHQEKH FQQYIIDRLV DQGWKLGDTK FYDTERAVYP EDLESWIKTS GQQEKWDKLE
RLNGAKTLEV LIARLVKALE KQGTIKVLRQ GFSIAGCGLI EMTEAAPEDQ RNALIIERYQ
ANILRVVPEL KYHPAQEFAI DLVLFINGLP VATVELKTDF TQSCEAAMDQ YRNDRLPYDS
KTKRREPLLA FKRGAVVHFA MSDSEIMMAT KLDGENTFFL PFNKGRKDES GTVHAGNPPG
DIKPDGNQEY PVAYFWESVC QPDAWLRIFH SFVYIEKKDV VDIQGNWLKK ETLIFPRFHQ
WTAVNQMLAD ARQNGTGMTY LCDHSAGSGK TSTISWTAHD LVKLREDNGD AVFNSVIIVT
DRNVLDGQLQ DAVKQIDHQF GVIAAIDRQK SSKPKSNQLS EALLAGTPIV IVTIQTFPYA
MEAIITDKAL KGKNFAVIID EAHNSQTGST AAKLQAALGM SGQGKMSTMT VDELLEQLQK
SRARPNNISY FAFTGTPKHS TLMLFGRPID PSQPASDDNP PKAFHLYTMR QAIEEKFILD
VLKGYVPYKT AFNLSKQVED SKRVSGKAAK RALAQWMSLH PTNVTQKVQF IVEHFTKNVA
HRLDGKAKAM VVTSSRAAAI RYKKAFDRYI EQHSEYGFIH SLIAFSGKMT GKQVIHQDDG
EFNNDVFIVD ENDVFTEQSM NPDLHGQDLR FAFDRPEYRV ILVTDKFQTG FDQPKLVAMY
VDKKIANHVE IVQTFARLNR IAPGKDEVFI IDFVNDPENV RKAFATYDNG AHIDEIQDLN
VVYEIKARLD EHDLYDEKDL AAFKEARFKT IRDITHTQSP QHKALYAATA GATALYNDKL
KMLRDGMATW EAAFEKAYAK GDEAGMKSAE HHQDEYAKQI KTLIGFKSDL GHFCRTYSYI
AQLIDFGDPE LENFAAFAKL LQKRLLHEAP EIVDLTGLVL TGFDINARQD KTEDEGEAPV
LKPTGAGGGG VAGDKPKFVK EIIERLNSLF GEATPIQDQV AFVNQISSIT GESDVVMAQV
ESNTREQAMK GNLPGAVQQA VVRALSSHQK LATQVLKSDR QGMSALVDVI YDLLRGATNI
DLDAD
//
