ID L0F8W5_DESDL Unreviewed; 688 AA.
AC L0F8W5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN OrderedLocusNames=Desdi_2857 {ECO:0000313|EMBL:AGA70269.1};
OS Desulfitobacterium dichloroeliminans (strain LMG P-21439 / DCA1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfitobacterium.
OX NCBI_TaxID=871963 {ECO:0000313|EMBL:AGA70269.1, ECO:0000313|Proteomes:UP000010797};
RN [1] {ECO:0000313|Proteomes:UP000010797}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG P-21439 / DCA1 {ECO:0000313|Proteomes:UP000010797};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Kruse T.,
RA de Vos W.M., Boon N., Smidt H., Woyke T.;
RT "Complete sequence of Desulfitobacterium dichloroeliminans LMG P-21439.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CP003344; AGA70269.1; -; Genomic_DNA.
DR RefSeq; WP_015263232.1; NC_019903.1.
DR AlphaFoldDB; L0F8W5; -.
DR STRING; 871963.Desdi_2857; -.
DR KEGG; ddl:Desdi_2857; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_9; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000010797; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:AGA70269.1};
KW Cilium {ECO:0000313|EMBL:AGA70269.1};
KW Flagellum {ECO:0000313|EMBL:AGA70269.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000010797};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 64..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 112..129
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 279..310
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 688 AA; 75387 MW; 8DE32AC2EB81A77F CRC64;
MATNISRRWY NNIDVLAAIF IVSIVVMMVI PIPPLLLDIL LTVSITSAVL TLMIAVFTKD
PLDFSVLPSL ILILTLFRLS LNVSTTRLIL ADAHAGNVIE QFGEFVVRGE PVVGFIIFAI
LVVVNFIVIT KGSERVSEVG ARFTLDAMPG KQMSIDADLN AGMITDLQAR DRRKKIQSEA
DFYGAMDGAS KFVKGDAIAA IIILFINIIG GFVTGIAMRG MDIMEALHTY TLLTIGDGLV
TQIPALLMST ATGLVVTRAA SETNLGQDLS SQLFRTPKAL YITAGVCIIL AMFGLPWVPL
LIVAIALVLL GRTMDRGSQQ NLVEETAAAR ETAIEESKKP ENVLNLLTID NMELELGYAL
IALVDVQQGG DLLDRIVLIR RQVASELGFI VPVIRVRDNM NLQPNQYSIK LRGAEVAGGE
IMADHYLAMS SGLGDDNIPG IPTKEPAFGL DAKWINAIYR EEVEMNGGTV VDAPTVLATH
ITEVIKSNAW EILSRQDVKT LLDHAREQAP AAVDDAMEHI NLGQMQKILS NLLRERVSIR
DMVTILETLA DYAGTTKDLD RLTEYVRQSL GRQIVQPLLG SNKELPVLTL EPKLEQQILD
SIQPSDYGSY MTLDPRVLQE VMQSLAREME KMILKGFNPV LVCAPVVRIN LKRVTERQLP
QLIVLSYNEL VHGVQVQAVG MVMTGNAS
//
