ID L0JZS4_9EURY Unreviewed; 755 AA.
AC L0JZS4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Transglutaminase-like enzyme, predicted cysteine protease {ECO:0000313|EMBL:AGB38261.1};
GN ORFNames=Natoc_2488 {ECO:0000313|EMBL:AGB38261.1};
OS Natronococcus occultus SP4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronococcus.
OX NCBI_TaxID=694430 {ECO:0000313|EMBL:AGB38261.1, ECO:0000313|Proteomes:UP000010878};
RN [1] {ECO:0000313|EMBL:AGB38261.1, ECO:0000313|Proteomes:UP000010878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP4 {ECO:0000313|EMBL:AGB38261.1,
RC ECO:0000313|Proteomes:UP000010878};
RG DOE Joint Genome Institute;
RA Eisen J., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Eisen J., Klenk H.-P.,
RA Klenk H.-P.;
RT "FINISHED of Natronococcus occultus SP4, DSM 3396.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003929; AGB38261.1; -; Genomic_DNA.
DR RefSeq; WP_015321703.1; NC_019974.1.
DR AlphaFoldDB; L0JZS4; -.
DR STRING; 694430.Natoc_2488; -.
DR GeneID; 14404172; -.
DR KEGG; nou:Natoc_2488; -.
DR eggNOG; arCOG02169; Archaea.
DR eggNOG; arCOG02963; Archaea.
DR eggNOG; arCOG11064; Archaea.
DR HOGENOM; CLU_022005_0_0_2; -.
DR OrthoDB; 18481at2157; -.
DR Proteomes; UP000010878; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.10.620.30; -; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025403; TgpA-like_C.
DR InterPro; IPR021878; TgpA_N.
DR InterPro; IPR002931; Transglutaminase-like.
DR PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR Pfam; PF13559; DUF4129; 1.
DR Pfam; PF11992; TgpA_N; 1.
DR Pfam; PF01841; Transglut_core; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AGB38261.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:AGB38261.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010878};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 452..522
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT REGION 536..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..614
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 80980 MW; 4092BF1DA9EA093E CRC64;
MSTDARGRTV SLDLERAVGT GPFRLLALAC VAALIGSYVW VLRDVTQVVG GTDALLVLVG
SMLVAATILA RAIRPRTATA AAVVLVVLGF TYYLEASGAG VGTALGATET ILTDTAALAT
GLPLLRMVEA GLWTLGFAPG PAFLSWYLAV RGRYALSAVP AGLALLFLVL TGDAGTTVTL
IGTVGAIGAV GFGELERRGG SIAQADLLAV VFAAIVVLSL SVTILPGEDA GPTFTGGGDG
TLEGTIDTAG ERSGISGQVD LSPEVRFTVE SDERSYWRTG VYDRFAGDEW VRSGPLSEYD
GSIDGPPGEG ETVTQRVTAE TELGVLPGAA QQVELEGPPT RHAEVSSHGQ PQPADTLVAG
DEYAVESVVV DPDPDELRAA GTDDPEHVTE DHDYLQLPED TSDEFEARAA ELTADADTRY
DAAVAIEDYL RSSKSYSLDV EQPPGNVAEE FLFEMDEGYC VYFATSMVQL LRAEEIPARY
ATGYTEGQEI DDGEYVVRGL DAHAWVEVYF PDHGWVAFEP TPGDAREDVH NDRLEDARED
GHDDVDTEDS EDVPVSDDEA ENESEAESDD EPDGTDDAPD GTDDAPDGTD DGETDETSDD
GTDDAPDESV GADDGIDPSE LVTISREQLA LALVGLVGLA AAVRHTGATA RARRELRLYW
HGRRGEPDED ARRAYRRLEE LLAREYRPRR RGESSRQYLA ALSAEHDIDE RAKRVARHYE
RATYGGGVDR EEADEAVDIV DELARERLSL RRRLH
//
