ID L0KF06_MESAW Unreviewed; 1516 AA.
AC L0KF06;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Mesau_01449 {ECO:0000313|EMBL:AGB43917.1};
OS Mesorhizobium australicum (strain HAMBI 3006 / LMG 24608 / WSM2073).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=754035 {ECO:0000313|EMBL:AGB43917.1, ECO:0000313|Proteomes:UP000010998};
RN [1] {ECO:0000313|Proteomes:UP000010998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 24608 / HAMBI 3006 / WSM2073
RC {ECO:0000313|Proteomes:UP000010998};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Gu W., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Reeve W.G., Howieson J.G., Tiwari R.P.,
RA O'Hara G.W., Atkins C.A., Ronson C.W., Nandasena K.G., Woyke T.;
RT "Complete sequence of Mesorhizobium australicum WSM2073.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP003358; AGB43917.1; -; Genomic_DNA.
DR STRING; 754035.Mesau_01449; -.
DR KEGG; mam:Mesau_01449; -.
DR eggNOG; COG0784; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG5002; Bacteria.
DR HOGENOM; CLU_003919_0_0_5; -.
DR Proteomes; UP000010998; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 4.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 6.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 4.
DR Pfam; PF12860; PAS_7; 3.
DR Pfam; PF00072; Response_reg; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 7.
DR SMART; SM00448; REC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 6.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 3.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000010998}.
FT DOMAIN 439..509
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 703..773
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 776..827
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 831..901
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 903..954
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 972..1192
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1210..1331
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1387..1505
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1336..1379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1264
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 1436
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1516 AA; 166816 MW; 0AC663DA87A14298 CRC64;
MAESDEAIGV RGKRKPGKAA APGGDGPSGV DMDCADALRQ LVEAGSDWIW ETDAELRFSW
LSQDYQAATG IDPAMVLGRF RFDFLNQVLK GNRGAAAHLE DLQAHRPFRD FVYELKGGRP
DCSWVLTSGF PRFDSEGKFV GYRGLGRNVT ALASAFEAMQ PAAGGDAVQH LADLERTMDA
MHMGVVLLDA RLDTLIVNKA YRDLSRIPDG AVTVGAPFSL LMELNRRNGI YGDIDEEQWQ
RYLATRIEEI KAGTVAPREF AHTDGRTMMF SVTALSGGKR LLTYYEVTEV KRRDAEIENA
NAKIAETFAN LRTMVDQMPI GVLVLDADMR AEVINRAFYD FWQIDARRAE TGCSFLDLME
ASRDIDPYGS DDATWHRHVA EREAEIRAGT AGARQFPRND GRTLISSMAP LAGGKRFISY
VDVTDMKDRE AELAEALEKA RLAEAVINGV KDPIFVKDDN LRFVFVNEAF AALFKQAPQA
MLGRPGSDFL GPDEVALFES SEREVLAGGQ QYEVEESFEA GGGIRSRIVR KNRVRMASGR
DYVAGFLFDI SDMKRRETEA EDARKHLASV LESLPAGVII YDRDDKFVFA NHRLQDTLPA
LKPFWQPGRT FREALEFGHS VGYFRSSGDP GIDSLYEGDS ERWLDGILAR YRLPNSSYER
LNADGRWYQV YDMRTGDGTF IGVRVDITDL KSREAALHDS MRQIDLFRHV MDELPVAAFI
KAQDLSIEFV NKAWCALTGL AKDDVIGRAD RQLFNGEEAE GFSQDDTDVV TNGNVREVEE
PVTHRDGTVR QLMTRKSRLV ATDGSVHLVG SSTDITDVKA REQALEESMR ENEVFRSLID
NVPVSIYAKR SDLRQFYVNK GWCDLTGFSK QEAIGKTDVE IFGPDGEAFV ASDLAVLRTG
ETQEIEETVR LPDGSVRHQF ARKGAMIASD GSLYLIGSTT DITELKQREA ELSEARRRAV
LADRAKSEFL ANMSHEIRTP MNGVLGMAEL LAKSNLDPKQ KTFTDIIVKS GNALLTIIND
ILDFSKIDAG QLVLDPAPFN LAEAIEDVAT LVSTRAKEKD LELIVRIEPR LESLFIGDVG
RIRQIVTNLL GNAVKFTDEG HVLVDVTGER VPTGTRLTIS VTDTGIGIPE EKLKLVFEKF
SQVDTSSTRR HEGTGLGLAI TSRLVDLMGG DIGVESAEGK GSTFWFTVTL PGAGQQSGQR
ITPVDVTGAR VLIVDDNAVN RAILTEQMTS WTFDSCAAES GAEGLKVLIA AAAYGVAVDC
VVLDYQMPEM SGAEMARIVR NTEGLADTPI IMLTSVDQSL ANTSYRDLGI DAQLIKPARS
SVLLETLVAT IQRHRHATSG HAVQPLTGEA PEASRPPPLA PSEQRAQLQP PQVRPRLPAT
AGGHRLDILV AEDNEVNQMV FTQILGETGY GFEIVGNGRK ALDAFGTLNP CMILMDVSMP
EMSGLEATAA IRLLEQETGT HVPIVGVTAH ALKGDRERCL EAGMDDYLPK PISPRALLEK
VERWVGAGRQ VHRNAG
//
