ID L0M186_ENTBF Unreviewed; 98 AA.
AC L0M186;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=DNA-binding protein Fis {ECO:0000256|HAMAP-Rule:MF_00166};
GN Name=fis {ECO:0000256|HAMAP-Rule:MF_00166};
GN OrderedLocusNames=D782_0437 {ECO:0000313|EMBL:AGB76500.1};
OS Enterobacteriaceae bacterium (strain FGI 57).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae.
OX NCBI_TaxID=693444 {ECO:0000313|EMBL:AGB76500.1, ECO:0000313|Proteomes:UP000011002};
RN [1] {ECO:0000313|EMBL:AGB76500.1, ECO:0000313|Proteomes:UP000011002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGI 57 {ECO:0000313|EMBL:AGB76500.1,
RC ECO:0000313|Proteomes:UP000011002};
RX PubMed=23469353; DOI=10.1128/genomeA.00238-12;
RA Aylward F.O., Tremmel D.M., Bruce D.C., Chain P., Chen A.,
RA Walston Davenport K., Detter C., Han C.S., Han J., Huntemann M.,
RA Ivanova N.N., Kyrpides N.C., Markowitz V., Mavrommatis K., Nolan M.,
RA Pagani I., Pati A., Pitluck S., Deshpande S., Goodwin L., Woyke T.,
RA Currie C.R.;
RT "Complete genome of Enterobacteriaceae bacterium strain FGI 57, a strain
RT associated with leaf-cutter ant fungus gardens.";
RL Genome Announc. 1:E00238-12(2013).
CC -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC upstream activation of rRNA promoters. {ECO:0000256|HAMAP-
CC Rule:MF_00166}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_00166}.
CC -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC {ECO:0000256|ARBA:ARBA00008559, ECO:0000256|HAMAP-Rule:MF_00166}.
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DR EMBL; CP003938; AGB76500.1; -; Genomic_DNA.
DR AlphaFoldDB; L0M186; -.
DR SMR; L0M186; -.
DR STRING; 693444.D782_0437; -.
DR KEGG; ebf:D782_0437; -.
DR PATRIC; fig|693444.3.peg.425; -.
DR eggNOG; COG2901; Bacteria.
DR HOGENOM; CLU_158040_3_0_6; -.
DR OrthoDB; 9802388at2; -.
DR Proteomes; UP000011002; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR HAMAP; MF_00166; DNA_binding_Fis; 1.
DR InterPro; IPR005412; Fis_DNA-bd.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR PANTHER; PTHR47918; DNA-BINDING PROTEIN FIS; 1.
DR PANTHER; PTHR47918:SF1; DNA-BINDING PROTEIN FIS; 1.
DR Pfam; PF02954; HTH_8; 1.
DR PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR PRINTS; PR01591; DNABINDNGFIS.
DR PRINTS; PR01590; HTHFIS.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|HAMAP-Rule:MF_00166};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_00166};
KW Reference proteome {ECO:0000313|Proteomes:UP000011002};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00166};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00166}.
FT DOMAIN 55..95
FT /note="DNA binding HTH"
FT /evidence="ECO:0000259|Pfam:PF02954"
FT DNA_BIND 74..93
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00166"
SQ SEQUENCE 98 AA; 11240 MW; 2E339BFCFCDB163C CRC64;
MFEQRVNSDV LTVSTVNSQD QVTQKPLRDS VKQALKNYFA QLNGQDVNDL YELVLAEVEQ
PLLDMVMQYT RGNQTRAALM MGINRGTLRK KLKKYGMN
//
