ID L0MYX6_9CICH Unreviewed; 374 AA.
AC L0MYX6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=V1R5 receptor {ECO:0000313|EMBL:BAM71553.1};
GN Name=V1R5 {ECO:0000313|EMBL:BAM71553.1};
OS Pundamilia azurea.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303519 {ECO:0000313|EMBL:BAM71553.1};
RN [1] {ECO:0000313|EMBL:BAM71553.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Piece of fin {ECO:0000313|EMBL:BAM71553.1};
RA Nikaido M., Ota T., Hirata T., Suzuki H., Satta Y., Aibara M.,
RA Mzighani S.I., Sturmbauer C., Hagino-Yamagishi K., Okada N.;
RT "Multiple Episodic Evolution Events in V1R Receptor Genes of East-African
RT Cichlids.";
RL Genome Biol. Evol. 6:1135-1144(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AB670553; BAM71553.1; -; Genomic_DNA.
DR AlphaFoldDB; L0MYX6; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24241; NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24241:SF186; NEUROPEPTIDE Y RECEPTOR TYPE 6-LIKE; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:BAM71553.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..361
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 208..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 41147 MW; DC9AC7859450D382 CRC64;
MEGLIEAIIR ALMFIAGILG NNWLAICSLP RHKSSIRTNE VLFINLAISN LITNYLVDLP
DTMADFAGRW FLGKTYCGVF CFCAGLSETS SIFTTFFISV FWHQKLVGSL KRGGAPVQMD
SLCLVGWLLA GSWTVAVVFS VPHYFFFTLE VANDSHEDCI EIFPNPNARQ IYEAIYLTLA
NALPMAGIVF ASAQIVITLL QNHQRIRSHN SDQTKEMVKE ERKRSESKRN KASVSIISGP
TTSKDLRDST STNHIYTGVP APSSPNRQPS GHSLHNAPQN CSVGAQPNLS RPSQIPSKPH
PNSSTQVRAA KSVVAVASVV LVCWLTHLLL HITNNIHTSS IVVEVSSYIA ASYTCIIPYI
FLHGVKKLTC SSKR
//
