ID   L1KR81_9ACTN            Unreviewed;       949 AA.
AC   L1KR81;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:EKX63000.1};
GN   ORFNames=STRIP9103_01664 {ECO:0000313|EMBL:EKX63000.1};
OS   Streptomyces ipomoeae 91-03.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=698759 {ECO:0000313|EMBL:EKX63000.1, ECO:0000313|Proteomes:UP000010411};
RN   [1] {ECO:0000313|EMBL:EKX63000.1, ECO:0000313|Proteomes:UP000010411}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91-03 {ECO:0000313|EMBL:EKX63000.1,
RC   ECO:0000313|Proteomes:UP000010411};
RA   Huguet-Tapia J.C., Durkin A.S., Pettis G.S., Badger J.H.;
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKX63000.1}.
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DR   EMBL; AEJC01000473; EKX63000.1; -; Genomic_DNA.
DR   RefSeq; WP_009327024.1; NZ_AEJC01000473.1.
DR   AlphaFoldDB; L1KR81; -.
DR   PATRIC; fig|698759.3.peg.6336; -.
DR   OrthoDB; 3229913at2; -.
DR   Proteomes; UP000010411; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EKX63000.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010411}.
FT   DOMAIN          59..217
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          338..501
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          263..284
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          663..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        265..284
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   949 AA;  105461 MW;  A5B3A5ABC6B3D6EC CRC64;
     MIVLLSVGPG TLESTMTEDL SPAERYAAAR RRAAEQATAL ASFREMYDFG LDPFQIEACQ
     ALEAGKGVLV AAPTGSGKTI VGEFAVHLAL KQGKKCFYTT PIKALSNQKY ADLCRRYGAD
     KVGLLTGDNS VNSDAPVVVM TTEVLRNMLY AGSQTLIGLG HVVMDEVHYL SDRFRGAVWE
     EVIIHLPESV TLVSLSATVS NAEEFGDWLD TVRGDTEVIV SEHRPVPLFQ HVLAGRRMYD
     LFEEGEGHKK AVNPDLTRMA RMEASRPSFQ DRRRGRAMRE ADRERERRQR SRIWIPSRPE
     VIERLDSEGL LPAITFIFSR AACEAAVQQC LYAGLRLNDD EARLKVRALV EERTATIPAE
     DLHVLGYYEW LEGLERGIAA HHAGMLPTFK EVVEELFVRG LVKAVFATET LALGINMPAR
     SVVLEKLVKW NGEQHADITP GEYTQLTGRA GRRGIDVEGH AVVLWQRGMN PDHLAGLAGT
     RTYPLRSSFK PSYNMAVNLV EQFGRHRSRE LLETSFAQFQ ADKSVVGISR QVQRNEEGLE
     GYKESMTCHL GDFEEYARLR RELKDRETEL AKQGAAQRRA EAAVALEKLK PGDVIHVPTG
     KYAGLALVLD PGLPAGRSNG HRGLEYHDGP RPLVLTAERQ VKRLASMDFP VPVEALERMR
     IPKSFNPRSP QSRRDLASAL RTKAGHLVPD RHRKRRAAAA DDREIARLRA ELRAHPCHGC
     NDREDHARWA ERYHRLKRDT AQLERRIEGR TNTIARTFDR IVALLTELDY LRGDEVTEHG
     KRLARLYGEL DLLASECLRA GVWEGLDPAE LAACVSALVY EARVGDDAMA PKLPSGKAKA
     ALGEMVRIWG RLDGLEEEFR ITQSEGVGQR EPDLGFAWAA YMWASGKGLD EVLREAEMPA
     GDFVRWCKQV IDVLGQVSAA APSGSTVAKS ARKAVDGLLR GVVAYSSVG
//