ID L1L7Q0_9ACTN Unreviewed; 762 AA.
AC L1L7Q0;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=MMPL family protein {ECO:0000313|EMBL:EKX68937.1};
GN ORFNames=STRIP9103_06992 {ECO:0000313|EMBL:EKX68937.1};
OS Streptomyces ipomoeae 91-03.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698759 {ECO:0000313|EMBL:EKX68937.1, ECO:0000313|Proteomes:UP000010411};
RN [1] {ECO:0000313|EMBL:EKX68937.1, ECO:0000313|Proteomes:UP000010411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91-03 {ECO:0000313|EMBL:EKX68937.1,
RC ECO:0000313|Proteomes:UP000010411};
RA Huguet-Tapia J.C., Durkin A.S., Pettis G.S., Badger J.H.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX68937.1}.
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DR EMBL; AEJC01000051; EKX68937.1; -; Genomic_DNA.
DR RefSeq; WP_009296930.1; NZ_AEJC01000051.1.
DR AlphaFoldDB; L1L7Q0; -.
DR PATRIC; fig|698759.3.peg.521; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000010411; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010411};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 172..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..614
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 676..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..326
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 762 AA; 79423 MW; 2E7E67F49DC2D775 CRC64;
MAALALWCVR HRLVAVLLWL LAFAGTVAGA AVAGSAYSND YKTPGTESSR AAELLSEGFP
RTSGDSATVV WHSVGGTVRA AAVEQTMTKT LDDIADLPGV AAVTDPYDGA DGGRISEDGR
TAYATVTFDK PAEDVDKAEA RAVVGTAKAA EGDGLQVELG GSAIGLTETT GGHLAEVVGV
LVAAVVLFLA FGSLAASLLP IATALVSVGT AYAGITLLGH AMTVADFAPM LGTLIGLGVG
IDYALFIVTR HRKGLKRGLP VEEAARNAVA TTGRAVVFAG ATVCIALLGM LILRLGFLNG
VAIAASLTVV LTVAASVTLL PALLSFIGTR ALGRRERRRL AEHGPEPELP TGFAARWSTF
VERHPKKLGA IALVVMALLA LPTLGLRLGT SDQGNDPKAT TTRQAYDLLA DGFGAGVNGP
LTLVTEVHGG ADKLALDNLD ASLRATDGVS TVTPVTYNTG GDTAYLTVVP DSSPQSERTS
DLVERLRDEV LPRAETGTDL DVHVGGVTAG YDDFADVIVG KLPLFVGVVI GLGCLLLLLA
FRSIGIPLKA AAMNVAAVAA AFGVVVAIFQ WGWGSELMGL GSAGPIEPFL PVIMVSVLFG
LSMDYQVFLV SRMYEEWLET GDNRRAVRVG LAETSRVINS AAVIMISVFL AFVLSGDRVI
AMFGIALASA VALDAFVLRT LLVPALMHLL GGANWWLPRW LDRRMPRISI EPPESRAAHE
RLAATTDAEA ADVLAGDTDV VDADAKDVRA KERQQDVRDI PG
//
