ID L1LBX2_THEEQ Unreviewed; 1312 AA.
AC L1LBX2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Reverse transcriptase domain containing protein {ECO:0000313|EMBL:EKX72831.1};
DE EC=2.7.7.49 {ECO:0000313|EMBL:EKX72831.1};
GN ORFNames=BEWA_013900 {ECO:0000313|EMBL:EKX72831.1};
OS Theileria equi strain WA.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=1537102 {ECO:0000313|EMBL:EKX72831.1, ECO:0000313|Proteomes:UP000031512};
RN [1] {ECO:0000313|EMBL:EKX72831.1, ECO:0000313|Proteomes:UP000031512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WA {ECO:0000313|EMBL:EKX72831.1,
RC ECO:0000313|Proteomes:UP000031512};
RX PubMed=23137308; DOI=10.1186/1471-2164-13-603;
RA Kappmeyer L.S., Thiagarajan M., Herndon D.R., Ramsay J.D., Caler E.,
RA Djikeng A., Gillespie J.J., Lau A.O., Roalson E.H., Silva J.C., Silva M.G.,
RA Suarez C.E., Ueti M.W., Nene V.M., Mealey R.H., Knowles D.P., Brayton K.A.;
RT "Comparative genomic analysis and phylogenetic position of Theileria
RT equi.";
RL BMC Genomics 13:603-603(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX72831.1}.
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DR EMBL; ACOU01000004; EKX72831.1; -; Genomic_DNA.
DR STRING; 1537102.L1LBX2; -.
DR EnsemblProtists; EKX72831; EKX72831; BEWA_013900.
DR VEuPathDB; PiroplasmaDB:BEWA_013900; -.
DR eggNOG; KOG1075; Eukaryota.
DR OrthoDB; 3261993at2759; -.
DR Proteomes; UP000031512; Unassembled WGS sequence.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR CDD; cd01650; RT_nLTR_like; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR35450; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR35450:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:EKX72831.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031512};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:EKX72831.1};
KW Transferase {ECO:0000313|EMBL:EKX72831.1}.
FT DOMAIN 545..811
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1290..1312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1312 AA; 152900 MW; 12715D9F955A9618 CRC64;
MCDDDTQMLI VTSENSTTEA ESASSEAFWT PMEISEEEDD QMEIIDLTPP NYQADEVEIL
LTGTPPSPSD NSIRVLEPKE VNSQLPEDSS PIEEPGSSDR TSCFTDEEEF CNNAAQDRLT
RAPGEMQCGP EYNQNNYLNK QVATCTTTQN RQGNKRPSKQ QRKENENNKI IALKVMLDGT
DEPEKIWPAC VLHKVQQSLG KVPKFGWQHI HEAYKARFSN DIDLEKLQDL ARKGLRNNLH
LKLPSDEELM LRADELPENS LKELRRKINI KEDINRKLVL MEQYEIEEAE RTYKIYSQRF
QETTFQYILD ELGSYLLEIS NQPRDFSEAT RILQAVQLSY HHVTYKEWEP SNWKENMEFK
IAGFKYTKEL IDREELYDLS REERGRAIQY MKNKGKILEN PQHRLEEKVA LDNNILIYQT
KIDRSEERIQ FNLDNSNFEK NTKKFFRNLL NQGQSRDHPS PVEMEIHWSP VWDARTINPE
KFERYLYLNP TVVREEKDFI SEEEFYEIIK GLPDWKACGV DGVYNFFIKR TTHLHPFLYK
LTKQACMEPH KIPQWFGKGI TYLIKKSDET TPSNYRPITC MSNLYKLVTK CVYRVLIGIV
QERRLLSEAQ LATVKGVQGA KEQALLNIAI NRAHKNNLKT SWLDIRKAFD SIDHKYLHAV
LDHLNIPDWI TNFIKHITSG WTIDVRCGKE PIMVKKVTRG ILQGDSLSPL LFVLCMDPLS
KILHSVYPTV KGKIGEKQEH GLNHLLFMDD IKLFAETDEI LKKMTDEVKM FCEASGLEIN
REKSATNSPL CEDTAVLLEG SAMYKYLGIM EDRSSIPSLE SWEKIRAEIL ARVEKLAKTK
LNGRNMFKAI NMFALSLLNY YTGLLRLLPD DFEALDLDIR KILVKHRIHY LNASPERLYL
KRDQCGRGLA SATFRSEKML LTFWDTLRKG SETSTRRALI MQIENEDLTH MSRIEGFVRR
KYENVNNGGL RIGDDNINEM QRRSLFHSLS QKRCHPIFFK QLNGDNLIDR KESALWLTHG
NISARDEAAY CALQDRNIFM GNYDKCKHCK GATATVDHLA TCCERKLAFD YTRRHNEVLK
CVSLHLCRMF NLIKRKKIKG YVMQETVTDG TNELRIDTAV KTDARITNNR PDIQLYDRRN
KRIFIVEVGI TCPTKVSDTE SHKQRKYDVL AKELCGIHNM PACTVPIVYS WDGLVTKYHA
KHLEKIAVPI KIRAYMQTRV LRTTLDSVTH DRRRGVEERE PEEKLEDIFE RFLGNLDKEE
KPLEEEEVEN ELEFSRDRVI RIRKKIKRRR TAASRRSEGP QNLRKIRRSQ EG
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