ID L1MG40_9CORY Unreviewed; 310 AA.
AC L1MG40;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Dihydrodipicolinate synthetase family protein {ECO:0000313|EMBL:EKX90223.1};
GN ORFNames=HMPREF9997_01438 {ECO:0000313|EMBL:EKX90223.1};
OS Corynebacterium durum F0235.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1035195 {ECO:0000313|EMBL:EKX90223.1, ECO:0000313|Proteomes:UP000010445};
RN [1] {ECO:0000313|EMBL:EKX90223.1, ECO:0000313|Proteomes:UP000010445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0235 {ECO:0000313|EMBL:EKX90223.1,
RC ECO:0000313|Proteomes:UP000010445};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX90223.1}.
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DR EMBL; AMEM01000018; EKX90223.1; -; Genomic_DNA.
DR RefSeq; WP_006063667.1; NZ_KB290831.1.
DR AlphaFoldDB; L1MG40; -.
DR STRING; 1035195.HMPREF9997_01438; -.
DR PATRIC; fig|1035195.3.peg.1293; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_049343_5_1_11; -.
DR OrthoDB; 3175637at2; -.
DR Proteomes; UP000010445; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000010445}.
FT ACT_SITE 138
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 166
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 212
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 310 AA; 32960 MW; 5C8B696696929C31 CRC64;
MSVSAYTGVI PPVVTPFNED FSIDRESLAT QVRRMIDAGV DGLFALGSSA EVAFLTRENR
RAVIETIVKA ADGKVPVLVG VIDTTTLRVA EHVADAVELG ASGLVATAPF YVRTHPNEIL
NHFRLIHEMA PELPLYLYQI PVSVHVTVSD DLILQLAEEG VIAGLKDSSG LDGATRALIE
KRNARNLTNF KVLTGSETTV DLNYFFGADG VVPGLGNVDP AGYVRLAAAC TAGDWDAARA
EQQRLNKLFQ IVFVGDGARM GGSSAGLGGF KAALQHLGVF TSGRMAPPHV ALNDEELATI
HSIVDQADLN
//
