ID   L1N194_9BACT            Unreviewed;       402 AA.
AC   L1N194;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   SubName: Full=Putative uracil permease {ECO:0000313|EMBL:EKX97273.1};
GN   ORFNames=HMPREF9151_02191 {ECO:0000313|EMBL:EKX97273.1};
OS   Hoylesella saccharolytica F0055.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Hoylesella.
OX   NCBI_TaxID=1127699 {ECO:0000313|EMBL:EKX97273.1, ECO:0000313|Proteomes:UP000010433};
RN   [1] {ECO:0000313|EMBL:EKX97273.1, ECO:0000313|Proteomes:UP000010433}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0055 {ECO:0000313|EMBL:EKX97273.1,
RC   ECO:0000313|Proteomes:UP000010433};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKX97273.1}.
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DR   EMBL; AMEP01000142; EKX97273.1; -; Genomic_DNA.
DR   RefSeq; WP_009161052.1; NZ_KB290960.1.
DR   AlphaFoldDB; L1N194; -.
DR   STRING; 1127699.HMPREF9151_02191; -.
DR   PATRIC; fig|1127699.3.peg.2004; -.
DR   HOGENOM; CLU_017959_1_2_10; -.
DR   OrthoDB; 9779092at2; -.
DR   Proteomes; UP000010433; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010433};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        114..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        292..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        320..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        353..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        376..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   402 AA;  42150 MW;  E50E63EBB863B81D CRC64;
     MNTTTLSPTK RFIVGVQFLF VAFGATVLVP LLVGLEPATA LMTAGLGTFI FHFITKGKVP
     IFLGSSFAFI APIISASKQW GMPGTLAGLL GVSLVYFVMS ALVKWQGKRL LDKLFPPVVI
     GPVIILIGLS LSSSAVDMAK SNWLLAFISL ITAILVLTMG RGLLKLVPVV CGISAGYIAA
     CCLGEVDFRP VAEASWFALP SGIAHFSLPD LSWEPLLFMI PVAIAPVIEH IGDVYVVGAV
     AEKDFTKDPG LHRTLLGDGL ACFASAFLAG PPVTTYSEVT GAMSITKVTS PAVIRIAAGT
     AIVFSVIGKL SALLRSIPQS VLGGIMLLLF GTIASVGLLN LMRHKVDLNQ TRNIIIIGVT
     LTMGIGGAVL SYGNFAISGI GLSAIVGITL NLCLPKEKEK KN
//