ID   L2GSI2_VAVCU            Unreviewed;       695 AA.
AC   L2GSI2;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Hsp70-like protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VCUG_01919 {ECO:0000313|EMBL:ELA46589.1};
OS   Vavraia culicis (isolate floridensis) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Pleistophoridae;
OC   Vavraia.
OX   NCBI_TaxID=948595 {ECO:0000313|EMBL:ELA46589.1, ECO:0000313|Proteomes:UP000011081};
RN   [1] {ECO:0000313|Proteomes:UP000011081}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=floridensis {ECO:0000313|Proteomes:UP000011081};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Becnel J., Sanscrainte N., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA   McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The genome sequence of Vavraia culicis strain floridensis.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR   EMBL; GL877439; ELA46589.1; -; Genomic_DNA.
DR   RefSeq; XP_008074935.1; XM_008076744.1.
DR   AlphaFoldDB; L2GSI2; -.
DR   STRING; 948595.L2GSI2; -.
DR   GeneID; 19879788; -.
DR   VEuPathDB; MicrosporidiaDB:VCUG_01919; -.
DR   HOGENOM; CLU_005965_2_1_1; -.
DR   InParanoid; L2GSI2; -.
DR   OMA; YAYHMKS; -.
DR   OrthoDB; 143at2759; -.
DR   Proteomes; UP000011081; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd10170; HSP70_NBD; 1.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375:SF395; HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED; 1.
DR   PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR   Pfam; PF00012; HSP70; 2.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR   SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU003322};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011081}.
FT   REGION          556..575
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          662..695
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   695 AA;  76117 MW;  10B58161079E0BB0 CRC64;
     MSSQNTSKET SKAIGIDLGT TYSCVCAYRN GELEVISNEE GARITPSIVA FDDEGNIVIG
     TAAEHRLTSN PDKVVYDVKR LIGRGYDSPV LESSIKKWPF RVVRWDNDRN STTDRPAKSD
     AVDNIRIEIM KGGKVMHYDP MEISGYVLGF LKRAAEAVLN SGVTTAVITV PAHFNDNQKE
     KTKMAAEIAG FKNVRLLNEP TAAALSYAYD KMRRKEANKE ETVLVFDLGG GTFDVSILKF
     EPPSESGAIA EVLNTEGDTF LGGVDFDNVL FEHCLALFLK QNPSVKKEEI KDRAKRRLRM
     ACEKAKRNLS AMNSTTIEIE CLHSDLGLCT SITRALFNSL CMKYFRRCMD RVKGCLLGLA
     KVKPDYTSEG FLTAASAANT SAINDAIAQV DRVIVVGGSS RIVKIREMLA EIFGEHKLDF
     SVHPDEAIAR GAAYQAALIS GGTSLDVECP LLLLDTVPLN ISIETLGGVA TNIIKKNTVI
     PTAKTEVFST ASDNQTSVTI NIYEGLGEMV EHNNLIGSFN LCGITPARRG MPQIEVTCDV
     DNNGILVVTA REKGSNKSEK LTVSNSNRKT TPEQLEEMHK KHKEFEEADR KKKENVSAKI
     EYEAMLYQLN EKVAEVPDQN VKSSLETSLK QHQEWLDAHP NADKDEYVTK KDELMGLLQQ
     VAGSAQGAAP GGFDASNFGG APPHSTTEPK VDEVD
//