ID L2GYK0_VAVCU Unreviewed; 270 AA.
AC L2GYK0;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=GPI-anchor transamidase {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=VCUG_00016 {ECO:0000313|EMBL:ELA48407.1};
OS Vavraia culicis (isolate floridensis) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Pleistophoridae;
OC Vavraia.
OX NCBI_TaxID=948595 {ECO:0000313|EMBL:ELA48407.1, ECO:0000313|Proteomes:UP000011081};
RN [1] {ECO:0000313|Proteomes:UP000011081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=floridensis {ECO:0000313|Proteomes:UP000011081};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Becnel J., Sanscrainte N., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The genome sequence of Vavraia culicis strain floridensis.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SIMILARITY: Belongs to the peptidase C13 family.
CC {ECO:0000256|ARBA:ARBA00009941}.
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DR EMBL; GL877404; ELA48407.1; -; Genomic_DNA.
DR RefSeq; XP_008073037.1; XM_008074846.1.
DR AlphaFoldDB; L2GYK0; -.
DR STRING; 948595.L2GYK0; -.
DR MEROPS; C13.005; -.
DR GeneID; 19877908; -.
DR VEuPathDB; MicrosporidiaDB:VCUG_00016; -.
DR HOGENOM; CLU_089387_0_0_1; -.
DR InParanoid; L2GYK0; -.
DR OMA; DNFPYFF; -.
DR OrthoDB; 1122658at2759; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000011081; Unassembled WGS sequence.
DR GO; GO:0042765; C:GPI-anchor transamidase complex; IEA:InterPro.
DR GO; GO:0003923; F:GPI-anchor transamidase activity; IEA:InterPro.
DR GO; GO:0016255; P:attachment of GPI anchor to protein; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR028361; GPI_transamidase.
DR InterPro; IPR001096; Peptidase_C13.
DR PANTHER; PTHR48067; GPI-ANCHOR TRANSAMIDASE; 1.
DR PANTHER; PTHR48067:SF1; GPI-ANCHOR TRANSAMIDASE; 1.
DR Pfam; PF01650; Peptidase_C13; 1.
DR PRINTS; PR00776; HEMOGLOBNASE.
PE 3: Inferred from homology;
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000011081};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..270
FT /note="GPI-anchor transamidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003960257"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ELA48407.1"
SQ SEQUENCE 270 AA; 31131 MW; F79D389925C688A4 CRC64;
MLFFGVLFLL LHGAEAKNYA VILNASQYYK NIRHVANIHV FYKILKSNGF TDNEIIVFTC
DDLVHDSRNF TKGYVILPDG GFDVPEFEGK PFTPLSFYNA VMGNHKKLID MDESSNILIY
MCGHGNRDFL KVHNKHFITS TELTNALCAL SRRGINKAFV IVDTCRAATL IDKNKLPKNI
VVLFTSRDDQ NSISSFSSNI TGQMTIDNFP YFFYKHIQYR LDMNIEDFFE EMMSVYDVES
DLIVWPERGW KIGEFFKQVK GESLLCKFVI
//
