ID   L5JPZ9_PTEAL            Unreviewed;      1832 AA.
AC   L5JPZ9;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Fibrocystin {ECO:0000313|EMBL:ELK00213.1};
GN   ORFNames=PAL_GLEAN10025329 {ECO:0000313|EMBL:ELK00213.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK00213.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
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DR   EMBL; KB031158; ELK00213.1; -; Genomic_DNA.
DR   STRING; 9402.L5JPZ9; -.
DR   eggNOG; ENOG502QR85; Eukaryota.
DR   InParanoid; L5JPZ9; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   CDD; cd00102; IPT; 1.
DR   CDD; cd00603; IPT_PCSR; 5.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR037524; PA14/GLEYA.
DR   PANTHER; PTHR46769:SF1; FIBROCYSTIN; 1.
DR   PANTHER; PTHR46769; POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1; 1.
DR   Pfam; PF01833; TIG; 8.
DR   SMART; SM00429; IPT; 5.
DR   SUPFAM; SSF56988; Anthrax protective antigen; 1.
DR   SUPFAM; SSF81296; E set domains; 6.
DR   PROSITE; PS51820; PA14; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT   DOMAIN          238..398
FT                   /note="PA14"
FT                   /evidence="ECO:0000259|PROSITE:PS51820"
FT   REGION          679..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1832 AA;  199334 MW;  9A5E8AAA94113846 CRC64;
     MDKMIVWLIS LKSIEMLFMA DSESGLFYPA NGFQLEIHLV NMTVSVLPSI PCDISPVFLD
     LPVVMCRTRS LLSEAHEGLY YLEVHSGGQV VGSPNPGPQD SCTFKFSRAQ TPIVYQVYPP
     SGVPGKLIHV YGWIITGKLE TFDFDADYID SYPIQEDHGL GTLQCRVEGN YIEILSVFPE
     TGSLGGRTDI TITGDFFDIP AQVTISGIPC DVRHVSPRKI ECTTRAPGEG ARLTAPQAGN
     RGLLFEVGYA AEGLDLTEAT PGYMRQIVPN ASSPFGFWSK EGQPFRARLS GFFVAPETNN
     YTFWIQADSQ ASLYFSRSED PRSKVKVASI RMGTADWFDS WEQSGDEGPW QQKTTKLELF
     GGARYYLEAE HHGRAPSRGM KIGVQIHNTW LNPDVVSTYL REKHQIRIRA QRLPEIQMVT
     VSGRGNFFLT WDNVSSQPIS ANATAHQIQT AIEELLAVKC QLEPLSANIL LRLGFEQGSE
     GFSCDGHLTS GTEPFCGRFS LYQPRYLILR PPAAQKGYRL DQYTHLCIAY KDRMHKILKL
     IVSFTIGLQS IIKKNITCDW SLMGTSSESW QFTCTDLWKT CVHPSAYLQV LLKNSPVVVH
     RIDLLPLAQE TGAFYMDEII IADTNLTVSQ ADSGTARPGG NLVESVSVVG SPPVYNVTSW
     LAGCGPELPL ITASSVPTEE AEEGSRKVQV TTQRLQRTSP PVGGHFRIQL SNTVIPDVPV
     NISASHLCQL LQNNTDDFTS RYLNVHDFTV MEDLKSCYEH VWTISWSIQV GDLPNFIRVS
     GENLTGVNPA ATTRVVYDGG VFLAPIFGDM LATANPCTQV VVRVNDIPAY CSGSCSFQYL
     EGSTPWVHSL WYSLDGDINL LVYITGTSFS GDSQAFQITV NKSNCKVIFS NQTNVVCQTN
     LLPVGVHRMS MFVRPFGRAI NASGEGLFLN VEPRLDAVDP SRAAETGGLW ATIRGSSLED
     ISLVLFGSQS CAINITTSNS QRIRCRVPPR GKDGPIVNVT VIRGDHSAVL PMAFTYVSSL
     NPVIMSLSRN RSNIAGGEIL FIGMALLVDY TNLDVEVYIK DTLAWVHAKT AQGLEVVLPP
     LPAGLHRISV SINGVDIYSA GVDLHIQYIT EVFSIEPCCG SLLGGTILSI SGIGFSREPG
     LVWVLVGNQS CNIVNLAETH IWCETSPASL PPEADILTVP APVEVWVGNL SITQGPAPSL
     VGKGFTFTYE VATTPVVTAV RGEITNSSLR LYVEGNNLSN SVILLGDLNC SLETQSFRGN
     TSLSGCSFPL HGLEAGVYPL RIRQKQMGFA NMSAAPQQLV MTPWITTISP TNGSACGGTV
     LMVRGLALNS RRRSVQVYLS GPFTCVILSL GAQMVLCQIK PVGDSLPGAS FTLNITILVN
     GLPSECHGNC TLFLKEETTP VVDALTTDIN GSLTTVLIRG QRLGTTADEP MVYLDDHLPC
     IATFFNASHV ACQISDLTPG LHYLSAVHTS NGYACSGNVS RHFYILPRVF HYFPKNFSIY
     GGGLLTIEGT ALRGQNSTVV YLGQQACLTV SISTELLQCF VPAGHGSVVL DIEIDGLLYQ
     MGVVGYSNAF TPELLSVSHT DGILTLVVAH ISGAVNVDIF IGMSPCVGVS GNSTVLQCVV
     PFLPAGEYQV RGYDRTRGWA SSALAFTSSI TITAVTENFG CLGGRIVHVF GAGFSPGNIS
     AAVCGFPCQV LANATVSAFS CLVRPLDVSL ASLCDLKHEE ESCETSSLTY VRCDLTVSVG
     TERLPESWPY LYICEESSQC HFAPDHWMES VFSTFSGLFI SPKVERDEVL IYNSSCNITM
     ETEAKMECET PNQPITAKIT EIRKSRGQNT QV
//