ID L5JRF3_PTEAL Unreviewed; 374 AA.
AC L5JRF3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Keratin, type I cuticular Ha4 {ECO:0000313|EMBL:ELK01522.1};
GN ORFNames=PAL_GLEAN10019568 {ECO:0000313|EMBL:ELK01522.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK01522.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KB031150; ELK01522.1; -; Genomic_DNA.
DR AlphaFoldDB; L5JRF3; -.
DR STRING; 9402.L5JRF3; -.
DR eggNOG; ENOG502RTXS; Eukaryota.
DR InParanoid; L5JRF3; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF97; KERATIN, TYPE I CUTICULAR HA1; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 56..353
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 60..130
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 159..204
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 265..352
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 374 AA; 42763 MW; B5CDA12E005664C8 CRC64;
MTHNCCLSNF SCRSSCLSRP CVATSCQNIP LPGACNIPAN VGNCGWFCEG SFNGSEKETM
QFLNDRLASY LEKVRQLERE NAELESRIQE RCQQQEPLMC SSYQSYFRTI EELQQKILCA
KSENARLVVQ IDNAKLASDD FRTKYEMERS SRQLVESDIN SLRRILDELT LCRADLEAQV
ESLKEELLCL KKNHEEEVNT LRCQIGDRLN VEVDAAPTVD LNRVLNETRC QYEALVETNR
RDVEEWYTTQ TQELNKQVVS SSEQLQTCQA EIIELRRTRN SLENTLTETE ARYSSQLSQV
QCMITNVESQ LAEIRSDLER QNQEYQVLLD VRARLECEIN TYRNLLESED CNLPCNPCAT
TNACGNSCGP CGSS
//
