ID L5JRG3_PTEAL Unreviewed; 491 AA.
AC L5JRG3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Keratin, type I cytoskeletal 39 {ECO:0000313|EMBL:ELK01532.1};
GN ORFNames=PAL_GLEAN10019581 {ECO:0000313|EMBL:ELK01532.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK01532.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KB031150; ELK01532.1; -; Genomic_DNA.
DR RefSeq; XP_006924722.1; XM_006924660.1.
DR AlphaFoldDB; L5JRG3; -.
DR STRING; 9402.L5JRG3; -.
DR GeneID; 102897397; -.
DR KEGG; pale:102897397; -.
DR CTD; 390792; -.
DR eggNOG; ENOG502SH7Y; Eukaryota.
DR InParanoid; L5JRG3; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF106; KERATIN, TYPE I CYTOSKELETAL 39; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 95..406
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 92..169
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 205..243
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 339..391
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 491 AA; 55325 MW; EA2D25B79C226F01 CRC64;
MDTKGCTTVS SSTPCQSCSR ITNFRIISSN TGCQRGGLEA NSCQPTGHIL RTLQSQGCQP
TPCFRPMPIC LINNFNACPS LDDCGWHGEG INSNEKETMQ TLNDRLANYL EKVRMLEREN
TELESKIQEE CNKELPVICP DYLSYYATIE ELQQKILCTK AENSRLVSQI DNTKLAADDL
RAKYEAEVSL RQLVEADANG LQQILNALTL GRADLEARVQ SLKEELLCLK NNHEEEINSL
QSQLGDRLNI EVTAAPSADL NQILQKMRCQ YESIVETNRR DVEQWFNTQM ELLNQQVVTS
SQQQQCCQKE IIELRRTVNA LEVERQAQHR TRDSQECILA ETEARYTALL AQIQCLIDNL
EAQLAEIRCA LERQNQEYEI LLDIKSRLEC EIATYRSLLE SSDGECPCNP CATKWEPSTC
TSSKARAMEC TAPVYTSSSA PRGIPEPCST CRALSRLLVK IRTITKEIKD GKVISSHEHV
QPCFIIRAAK A
//
