ID L5JS25_PTEAL Unreviewed; 450 AA.
AC L5JS25;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Tubulin delta chain {ECO:0000256|ARBA:ARBA00014184};
DE AltName: Full=Delta-tubulin {ECO:0000256|ARBA:ARBA00030594};
GN ORFNames=PAL_GLEAN10019804 {ECO:0000313|EMBL:ELK01737.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK01737.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000256|ARBA:ARBA00004138}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriole
CC {ECO:0000256|ARBA:ARBA00004114}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the tubulin family.
CC {ECO:0000256|ARBA:ARBA00009636, ECO:0000256|RuleBase:RU000352}.
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DR EMBL; KB031150; ELK01737.1; -; Genomic_DNA.
DR RefSeq; XP_006924960.1; XM_006924898.2.
DR RefSeq; XP_006924961.1; XM_006924899.2.
DR RefSeq; XP_015454878.1; XM_015599392.1.
DR AlphaFoldDB; L5JS25; -.
DR STRING; 9402.L5JS25; -.
DR GeneID; 102888789; -.
DR KEGG; pale:102888789; -.
DR CTD; 51174; -.
DR eggNOG; KOG1374; Eukaryota.
DR InParanoid; L5JS25; -.
DR OrthoDB; 5476360at2759; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR CDD; cd02189; delta_zeta_tubulin-like; 1.
DR Gene3D; 3.40.50.1440; Tubulin/FtsZ, GTPase domain; 1.
DR InterPro; IPR002967; Delta_tubulin.
DR InterPro; IPR008280; Tub_FtsZ_C.
DR InterPro; IPR000217; Tubulin.
DR InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR InterPro; IPR017975; Tubulin_CS.
DR InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR PANTHER; PTHR11588; TUBULIN; 1.
DR PANTHER; PTHR11588:SF4; TUBULIN DELTA CHAIN; 1.
DR Pfam; PF00091; Tubulin; 1.
DR PRINTS; PR01224; DELTATUBULIN.
DR PRINTS; PR01161; TUBULIN.
DR SMART; SM00864; Tubulin; 1.
DR SUPFAM; SSF55307; Tubulin C-terminal domain-like; 1.
DR SUPFAM; SSF52490; Tubulin nucleotide-binding domain-like; 1.
DR PROSITE; PS00227; TUBULIN; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000352};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU000352};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000352}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 47..247
FT /note="Tubulin/FtsZ GTPase"
FT /evidence="ECO:0000259|SMART:SM00864"
SQ SEQUENCE 450 AA; 50706 MW; 6CA02812586240BB CRC64;
MSIVTLQLGQ CGNQIGFEVF DALFSDAHYH QGLCSKRENE AYQASCKERF FSEEENGVPI
ARAVLVDMEP KVINQTLSKA AQSGRWKYGQ HSCFCQKQGS GNNWAYGYSV HGPRHEESIM
NLIQKEVEKC DSLSGFFIIM SMAGGTGSGL GAFVTQNLQD QYSNSLKMNQ IIWPYGTGEV
IVQNYNSILT LSHLYRSSDA LLVHENDAVH KICAKLMNIK QISFSDINQV LAHQLGSVFQ
PTYSVEGSFH YRRNPLGDLM ENLVPHPEFK MLGIRNIPQM SENSLAYSTF TWAGLLKHLR
QMLISNAKME EGINWHVRPP VSGLPTLSKE LHFNTSIANL VILRGKSVHS ADLGGFKDPA
LYTSWLEPDN AFSVWKTQRA FSKYEKSAAL VSNSQFLVKP LDMIVGKAWN MFASKAYIHQ
YTKFGIEEED FLDSFTLLEQ VIASYCNLRF
//
