ID L5KLA1_PTEAL Unreviewed; 354 AA.
AC L5KLA1;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Cdc42 effector protein 4 {ECO:0000313|EMBL:ELK12409.1};
GN ORFNames=PAL_GLEAN10014790 {ECO:0000313|EMBL:ELK12409.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK12409.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Endomembrane system
CC {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004184}.
CC -!- SIMILARITY: Belongs to the BORG/CEP family.
CC {ECO:0000256|ARBA:ARBA00010770}.
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DR EMBL; KB030661; ELK12409.1; -; Genomic_DNA.
DR RefSeq; XP_006912322.1; XM_006912260.2.
DR AlphaFoldDB; L5KLA1; -.
DR STRING; 9402.L5KLA1; -.
DR GeneID; 102886740; -.
DR KEGG; pale:102886740; -.
DR CTD; 23580; -.
DR eggNOG; ENOG502QRD6; Eukaryota.
DR InParanoid; L5KLA1; -.
DR OrthoDB; 4097104at2759; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
DR InterPro; IPR029273; Cdc42_effect-like.
DR InterPro; IPR000095; CRIB_dom.
DR PANTHER; PTHR15344:SF14; CDC42 EFFECTOR PROTEIN 4; 1.
DR PANTHER; PTHR15344; CDC42 EFFECTOR PROTEIN BORG; 1.
DR Pfam; PF14957; BORG_CEP; 1.
DR Pfam; PF00786; PBD; 1.
DR SMART; SM00285; PBD; 1.
DR PROSITE; PS50108; CRIB; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 27..41
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT REGION 59..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 37729 MW; FACDBE45C0B2D1C4 CRC64;
MPILKQLVSS SVHSKRRSRV DLTAEMISAP LGDFRHTMHV GRAGDAFGDT SFLNSKAGEL
EGESQDEQAA SSSSKRGLLS RKFRSSKRSQ SVTRGDREQR DMLGSLRDSA LFVKNAMSLP
QLNEKEAAEK GSSKLPKSLS SSPVKKANGG EGDHQAAGVG EVPRRNGASA PHSPDPLLDE
QAFGDLTDLP VVPKASFGLK HAESIMSFHI DLGPSMLGDV LSIMDKEEWE PEEEDGGYRG
SEDPGSLSQA PPSGAAAPPL ARQEGKAGRD SPPPSSQALQ DEGWGAAAPS PGSARSVGSH
TTRDSSSLSS CTSGVLEERS PAFRGPDRAR GPPPRQQDKE FSFMDEEEED EIRV
//
