ID L5KLM3_PTEAL Unreviewed; 1417 AA.
AC L5KLM3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|EMBL:ELK12425.1};
GN ORFNames=PAL_GLEAN10014818 {ECO:0000313|EMBL:ELK12425.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK12425.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KB030661; ELK12425.1; -; Genomic_DNA.
DR STRING; 9402.L5KLM3; -.
DR eggNOG; KOG0059; Eukaryota.
DR InParanoid; L5KLM3; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF120; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 9; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:ELK12425.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 166..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 422..658
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1081..1314
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1417 AA; 160182 MW; 812F4C7769FCFB31 CRC64;
MPAVDLGRVD NFNDSNYVIA FAPESKTTQE IMNKVASAPF MKGRTIMGWP DEKSMNKLDL
NYSMDAVRVI FNDNFSYHLK FFWGGRIPKM KEHRDHSAHC QTVDEKVTCE GSVFWKKGFI
AFQAAINAAI IEITTNHSVM EELMSVTGIN MKILPFIAQE GITTDFFIFF CIISFSTFIY
YVSVNVTQER QYMKSLMTMM GLRESAFWLS WGLMYAGFIF IMATLMALVV KSTHVVVLTG
FAVVFTLFLL YGLSLITLAF LMSVLVKKPF LSGLVVYLLT VCWGSLGFTA LYRHLPAFLE
WTLCLLSPFA FTAGMAQLLH LDYDVNANIH LDSSNNLNLI IAILFMLVFD TLLYLVLTLY
FDKILPTEYG RRRSPCFFLK SSFWFQHQKV DHVALENELD LDPSSNDAFE PVPPEFRGKE
AIRIKNLKKE YKKGKNERVE ALKGLVFDIY EGQITALLGH SGAGKTTLLN MLSGLSVPTS
GSVTIYNHSP SEAADLETVS KLTGVCPQSN VQFGFLTVRE NLQLFAEIKG IQPHEVKQEV
QRVLRDLEME SIQDILAQNL SGGQKRKLTF GIAILGDPQI LLLDEPTAGS DPLSRHRVWS
LLKERKLDRV ILFSTQFMDE ADILADRKVF ISNGKLKCAG SSLFLKKKWG IGYHLSLHLN
EMCNPDNVTS LVKQHIPDAK LTAQSEEKLV YTLPLERTNK FPDLYKDLDR CSNQGIENYG
VSMTTLNEVF LKLEGKSAMD ESDSGIWGQL QSDRTKDSGS LVELEQLLSS CHETKKAVRG
MVLWRQQVCA IAKVRFLKLK NEKKTLMTIL LLLGISFFPQ LLEHLFYELY KKSYSWGLSP
NMYFHSPGQP PQAPLTHLLV INKTGSSIEN FIHSLRQQNI ALEVDAFGTR YGPNESSYNG
AITVSGDDKD HRFSIACNTK RLNCFPVLMD IISNGLLGIL NSSERIQTDR STYFEEHTSD
EYGYMSNAFF WIPVAACFTP YIAMSSIGDY KKKTHSQLWI SGLYPSAYWF GQALVDSPLY
FLILLLMQIM DYIFNPDEIM FIIQNLLIQI SPDSVDYVGS SEHYILYLAL LIQPVIVASC
LRKEYAGKKK NCFAKKKKKV ATRNVSFCVK KGEVFGLLGH NGAGKSTTIQ MITGDKKPTS
GQVTLKGSSE GDDLGFLGYC PQENALWPNL TVREHLEVFA AVKGLRKADA AVAITRLVGA
LQLQDQQKRP VKALSEGIKR KLCFALSILG NPPVVLLDEP STGMDPEGQQ RMWQAIRATF
RNTERGALLT THYMAEAEAV CDRVAIMVSG RLRCIGSIQH LKSKFGKDYL LEMKVKTLSQ
VEPLHSEILR LFPQAARQER YSSLMVYKLP VEDVRPLSQA FFKLEIVKQN FDLEEYSLSQ
STLEQVFLEL SKEQELEDFD DELHHSVKWK LLPQEEP
//
