ID L5M5A4_MYODS Unreviewed; 2157 AA.
AC L5M5A4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Trafficking protein particle complex subunit 10 {ECO:0000313|EMBL:ELK33834.1};
DE Flags: Fragment;
GN ORFNames=MDA_GLEAN10004966 {ECO:0000313|EMBL:ELK33834.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK33834.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat PWP2 family.
CC {ECO:0000256|ARBA:ARBA00010226}.
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DR EMBL; KB103804; ELK33834.1; -; Genomic_DNA.
DR eggNOG; KOG1931; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProt.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR027145; PWP2.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR007148; SSU_processome_Utp12.
DR InterPro; IPR022233; TRAPP_II_complex_TRAPPC10_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19858:SF0; PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG-RELATED; 1.
DR PANTHER; PTHR19858; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF12584; TRAPPC10; 1.
DR Pfam; PF04003; Utp12; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 1056..1232
FT /note="TRAPP II complex TRAPPC10 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12584"
FT REPEAT 1419..1451
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1604..1636
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1646..1687
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1732..1765
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 2005..2109
FT /note="Small-subunit processome Utp12"
FT /evidence="ECO:0000259|Pfam:PF04003"
FT REGION 1186..1209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1472..1495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2118..2157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ELK33834.1"
SQ SEQUENCE 2157 AA; 241764 MW; 919C018A8CB44C0B CRC64;
PLYSCLGAGD QNLFTSIYPT LSQQLPREPM EWRRSYGRAP KMIHLESNFV QFKEELLPKE
GNKALLTFPF LHIYWTECCD TEVYKATVKD DLTKWQNVLK AHSSVDWLIV VVENDAKKKN
KTNILPRTSI VDKIRNDFCN KQSDRCVVLN DPLKDSSRTQ ESWNAFLTKL RTLLLMSFTK
NLGKFEDDMR TLREKRTEPG WSFCEYFMVQ EELAFVFEML QQFEDALVQY DELDALFSQY
VVNFGAGDGA NWLTFFCQPV KSWNGLTLRK PIDMEKRELI QRQEATLLDL RSYLFARQCT
LLLFLQRPWE VAQRALELLH SCVQELKLLE VSVPPGALDC WVFLSCLEVL QRIEGCCDRA
QIDSNIAHTV GLWSYATEKL KSLGYLCGLV SEKGPNSEDL NRTVDLLAGL GAERPETANT
AQSPYKKLKE ALSSVEAFEK HYLDLSHATI EMYTSIGRIR SAKFVGKDLA EFYMKKKSPQ
KAETYLQGAL KNYLAEGWAL PITHTRKQLA ECQKHLGQIE NYLQTSSLLA SDHHLTEEER
KYFCQEILNF ASEKTDSSGH KVVLPMHSFA HLRDLRFTPS NAVVHVGGVL SVEITVCSQM
PVPVHMDQIA ISVHFSIEKN SYRKTAEWLT KHKTSNGIIN FPMETSPFPA SQNSLPALEL
YEMFERSPSD NSLNTTGIIC KNVHMLLRRQ ESSTALDTPS GVALDDGAPV LKCCGVTLEP
GANTITFRTQ AKEPGTYMLR QLCASAGPVC FVLPHLYPLA QYDVYSQEPQ LHVEPLADSL
LAGIPQKVKF TVTTGHYTVK NGDSLQLSNV EAMLILCHAE NKAVIYSNTR EKASDASLRV
QSSDKVTSIS LPAAPAYHMI EFELEVLSLP SAPAAGGEAG STMLGMTEAQ RKPKDTQKAD
HCMATTDHKV SIECPWSIYS TVIALTFSVP FRTTHAVLSA GTRKYIQVCV QNLSELDFRL
SDSDLVDTGD STDLQLLPLN TKSQQHICSR QSVFFVWELT WTREPPPSLH GRFSMEFRPA
SEEGLSISLK PYTYEFQVEN FFTLYTVKAE ILPPVGTELC RTGSLCALEV SITRLSDLLE
VDRDEALTES DEYFSTKLMY EVVDNSSNWA VCGKSSGVIS MPVVAQATHR VHMEVMPLFA
GYLPLPDVRL FKYLPHHSAH SSQLDADSWI ENDSLSVDKH VDDQLDSSSI KSRGSVHSAA
SSEHKGLPMP RLQALPPGQV FNSSTGMQIL VIPSKDDHVL EFSNLLGTVY RRGNLNFTCD
GNSVISPVGN RVTVFDLKNN KSNTLPLTTR YNVKCVGLSP DGRLAIIVDE GGNALLVSLV
CRSVLHRFHF KGSVHSVSFS PDGRKFVITK GNIAQMYHAP GRKREFNAFV LDKTYFGPYD
ETTHIDWTDD SRCFAVGSKD MSTWVFGAER WDNVIYYALG GHKDAIVACF FESNSLDLYT
LSQDGALCVW QCDTPPEGLR LKAPTGWKAD LLQREEEEEE EEEEEEERET TVRGKATPAL
EEQQGKVKYS RLAKYFFNKE GDFNNLTAAA YHKKIHLLVT GFASGIFHLH ELPEFNLIHS
LSISDQRIES VAINSSGDWI ALGCSGLGQL LVWEWQSESY VLKQQGHFNS MVSLAYSPDG
QYIVTGGDDG KVKVWNTLSG FCFITFTEHS SGVTGVTFTA TGYVIVTSSM DGTVRAFDLH
RYRNFRTFTS PRPTQFSCVA VDSSGEIVCA GAQDSFEIFI WSMQTGRLLE VLSGHEGPIS
GLCFNPMKSI LASASWDKTV RLWDMVDSWR TTETLALTSD ALAVTYRPDG AELAVATLNA
QITFWDPENA VQTGSIEGRH DLKTGRKELD KITAKHSAKG KAFTTLCYSA DGQSVLAGGM
SKFVCIYHVR EQILRKKFEI SCNLSLDAME EFLNRRKMTE FGNLALIDQD AGEEDGVAIP
LPGVRKGDMS SRHFKPEIRV TSLRFSPTGR CWAATTTEGL LIYSLDTQML FDPFELDTSV
TPGRIRAALR QRDFTRAILM AVRLNEKLLL QETLESVPWD EIDVISSSLP ELYVEKVLEF
LASSFEVSRH LEFYLIWTQK LLMAHGQKLK SRAGKLLPAV QFLQKSIQRH LDDVSKLCDW
NRYNIQYALA VSKQRGMKRP SEPLGSEEEA DASDDEDSLR LLGGGHGDGD DGDTLLV
//
