ID L5N4G4_9BACI Unreviewed; 74 AA.
AC L5N4G4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Transcription attenuation protein MtrB {ECO:0000256|HAMAP-Rule:MF_00798};
DE AltName: Full=Trp RNA-binding attenuation protein {ECO:0000256|HAMAP-Rule:MF_00798};
DE Short=TRAP {ECO:0000256|HAMAP-Rule:MF_00798};
DE AltName: Full=Tryptophan RNA-binding attenuator protein {ECO:0000256|HAMAP-Rule:MF_00798};
GN Name=mtrB {ECO:0000256|HAMAP-Rule:MF_00798};
GN ORFNames=D479_15367 {ECO:0000313|EMBL:ELK45340.1};
OS Halobacillus sp. BAB-2008.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=1246484 {ECO:0000313|EMBL:ELK45340.1, ECO:0000313|Proteomes:UP000010769};
RN [1] {ECO:0000313|EMBL:ELK45340.1, ECO:0000313|Proteomes:UP000010769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BAB-2008 {ECO:0000313|EMBL:ELK45340.1,
RC ECO:0000313|Proteomes:UP000010769};
RX PubMed=23469348;
RA Joshi M.N., Pandit A.S., Sharma A., Pandya R.V., Saxena A.K.,
RA Bagatharia S.B.;
RT "Draft Genome Sequence of the Halophilic Bacterium Halobacillus sp. Strain
RT BAB-2008.";
RL Genome Announc. 1:E00222-12(2013).
CC -!- FUNCTION: Required for transcription attenuation control in the Trp
CC operon. This trans-acting factor seems to recognize a 10 bases
CC nucleotide sequence in the Trp leader transcript causing transcription
CC termination. Binds the leader RNA only in presence of L-tryptophan.
CC {ECO:0000256|HAMAP-Rule:MF_00798}.
CC -!- SUBUNIT: Oligomer of 11 identical subunits arranged in doughnut-like
CC structure. {ECO:0000256|ARBA:ARBA00011104, ECO:0000256|HAMAP-
CC Rule:MF_00798}.
CC -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000256|ARBA:ARBA00010027,
CC ECO:0000256|HAMAP-Rule:MF_00798}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELK45340.1}.
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DR EMBL; ANPF01000069; ELK45340.1; -; Genomic_DNA.
DR RefSeq; WP_008638573.1; NZ_ANPF01000069.1.
DR AlphaFoldDB; L5N4G4; -.
DR PATRIC; fig|1246484.3.peg.3126; -.
DR eggNOG; ENOG5032Z9Y; Bacteria.
DR OrthoDB; 2111980at2; -.
DR Proteomes; UP000010769; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.60.40.50; TRAP-like; 1.
DR HAMAP; MF_00798; Trp_attenuator; 1.
DR InterPro; IPR000824; MtrB.
DR InterPro; IPR016031; Trp_RNA-bd_attenuator-like_dom.
DR InterPro; IPR023558; Trp_RNA-bd_attenuator_dom.
DR Pfam; PF02081; TrpBP; 1.
DR PRINTS; PR00687; TRPRNAAP.
DR SUPFAM; SSF51219; TRAP-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000010769};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00798};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00798};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00798}.
FT DOMAIN 5..72
FT /note="Tryptophan RNA-binding attenuator protein"
FT /evidence="ECO:0000259|Pfam:PF02081"
SQ SEQUENCE 74 AA; 8129 MW; 6840CCC03B9DFB8F CRC64;
MSAPNNDFFV IKALEDGVNV IGLTRGTDTR FHHSEKLDKG EVMIAQFTEH TSAVKVRGKA
VIQTSHGEMT NEAD
//
