ID L7F008_9ACTN Unreviewed; 507 AA.
AC L7F008;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=TldD/PmbA family protein {ECO:0000313|EMBL:ELP64316.1};
GN ORFNames=STRTUCAR8_02649 {ECO:0000313|EMBL:ELP64316.1};
OS Streptomyces turgidiscabies Car8.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698760 {ECO:0000313|EMBL:ELP64316.1, ECO:0000313|Proteomes:UP000010931};
RN [1] {ECO:0000313|EMBL:ELP64316.1, ECO:0000313|Proteomes:UP000010931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Car8 {ECO:0000313|EMBL:ELP64316.1,
RC ECO:0000313|Proteomes:UP000010931};
RX PubMed=21087627; DOI=10.1016/j.plasmid.2010.11.002;
RA Huguet-Tapia J.C., Badger J.H., Loria R., Pettis G.S.;
RT "Streptomyces turgidiscabies Car8 contains a modular pathogenicity island
RT that shares virulence genes with other actinobacterial plant pathogens.";
RL Plasmid 65:118-124(2011).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELP64316.1}.
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DR EMBL; AEJB01000462; ELP64316.1; -; Genomic_DNA.
DR RefSeq; WP_006380671.1; NZ_AEJB01000462.1.
DR AlphaFoldDB; L7F008; -.
DR STRING; 85558.T45_07958; -.
DR PATRIC; fig|698760.3.peg.6821; -.
DR Proteomes; UP000010931; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF10; CONSERVED PROTEIN; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000010931}.
FT DOMAIN 33..97
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 253..498
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 507 AA; 54673 MW; 72B0C9B13B0D342B CRC64;
MAHEVDQSFL ALPLRALADA ALARARALGA DHADFRFERV RSASWRLRDA KPSGSSDTTD
LGYAVRVVHG GTWGFASGVD LSMDAAAKVA SQAVAMAKLS AQVIKAAGSD ERVELAAEPV
HSDKTWVSSY EIDPFGVPDE EKAGLLAEWS GRLLSANGVN HVDASLLTVH ENKFYADTAG
TVTTQQRVRL HPQFTAVSVD ESSGEFDSMR TIAPPVGRGW EYLTGRGWDW ESELEQIPEL
LAEKMRAPSV EAGLYDLVVD PSNLWLTIHE SIGHATELDR ALGYEAAYAG TSFATFDQLG
KLRYGSELMN VTGDRTAEHG LATIGYDDEG VAGQSWDLVK DGTLVGYQLD RRIAKLTGFE
RSNGCAYADS PGHVPVQRMA NVSLRPDPGG LATEDLIGGV DRGIYVVGDR SWSIDMQRYN
FQFTGQRFFK IENGRITGQL RDVAYQATTT DFWGSMAAVG GPQTYVLGGA FNCGKAQPGQ
VAAVSHGCPS ALFKGVNILN TTQEAGR
//
