ID L7FGE1_9ACTN Unreviewed; 550 AA.
AC L7FGE1;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=STRTUCAR8_04389 {ECO:0000313|EMBL:ELP70254.1};
OS Streptomyces turgidiscabies Car8.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698760 {ECO:0000313|EMBL:ELP70254.1, ECO:0000313|Proteomes:UP000010931};
RN [1] {ECO:0000313|EMBL:ELP70254.1, ECO:0000313|Proteomes:UP000010931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Car8 {ECO:0000313|EMBL:ELP70254.1,
RC ECO:0000313|Proteomes:UP000010931};
RX PubMed=21087627; DOI=10.1016/j.plasmid.2010.11.002;
RA Huguet-Tapia J.C., Badger J.H., Loria R., Pettis G.S.;
RT "Streptomyces turgidiscabies Car8 contains a modular pathogenicity island
RT that shares virulence genes with other actinobacterial plant pathogens.";
RL Plasmid 65:118-124(2011).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELP70254.1}.
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DR EMBL; AEJB01000097; ELP70254.1; -; Genomic_DNA.
DR AlphaFoldDB; L7FGE1; -.
DR STRING; 85558.T45_04347; -.
DR PATRIC; fig|698760.3.peg.1097; -.
DR Proteomes; UP000010931; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PIRSF; PIRSF001093; B-hxosamndse_ab_euk; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ELP70254.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010931}.
FT DOMAIN 9..142
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 146..493
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 524..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 324
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 550 AA; 60629 MW; E6E2D8D2E3B28173 CRC64;
MTDVNDVNEL VPAPVAVRDV RAAGGFLFDE NTVIDAGPGT EAAAGWLRGV LGAATGLALP
PGAGDDGETV RLRVQLEDAG HLGPEGYKLY VNGDDVTIHG GGPAGVFWGA QTLRQLLGPD
AFRRAPVTPG RQWLVPGTFV EDSPRFRWRG LMLDVARHFM PKEGVLRYLD LMAAHKLNVF
HFHLTDDQGW RVEIKRYPRL TEVGSWRART KFGHRASPLW EEKPHGGFYT QDDIREIVAY
AAERHISVVP EIDVPGHSQA AIAAYPELGN TDVIDTTSLS VWDTWGINKN VLAPTDNTLR
FFEGVFEEVL GLFPGEFVHI GGDECPKDQW RQSPTAQARI HELGLVDEDG LQSWFVGHFD
KWLTARGRRL IGWDEILEGG LAPGAAVSSW RGYAGGITAA RAGHDVVMCP EQQVYLDHRQ
HDGTDEPVPI GYVRTLEDVF RFEPVPPELG PKEALHVLGT QANLWTEVME DAGRVDYQAF
PRLAAFAEVA WSALPAPAAR DFADFERRMT AHYGRLDALG VGYRPPTGPR PWQQRPGVLG
RPIEGTPPNV
//
