ID L7MS37_HORSE Unreviewed; 210 AA.
AC L7MS37;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Cullin-4A-like protein {ECO:0000313|EMBL:AEB61292.1};
DE Flags: Fragment;
GN Name=CUL4A {ECO:0000313|EMBL:AEB61292.1};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|EMBL:AEB61292.1};
RN [1] {ECO:0000313|EMBL:AEB61292.1}
RP NUCLEOTIDE SEQUENCE.
RA Waegele B., Farthmann B., Nyakatura G., Heubner D., Mewes H.-W.,
RA Steinbach F.;
RT "Analysis of a normalized equine cDNA library using deep sequencing.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
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DR EMBL; HQ890137; AEB61292.1; -; mRNA.
DR AlphaFoldDB; L7MS37; -.
DR HOGENOM; CLU_004747_7_2_1; -.
DR UniPathway; UPA00143; -.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF68; CULLIN-4A; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 2: Evidence at transcript level;
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 1..83
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEB61292.1"
SQ SEQUENCE 210 AA; 24640 MW; 59B5BE50DF3E167B CRC64;
LQEVFKTFYL GKHSGRKLQW QTTLGHAVLK AEFKEGKKEF QVSLFQTLVL LMFNEGDEFS
FEEIKTATGI EDSELRRTLQ SLACGKARVL IKSPKGKEVE DGDKFIFNGE FKHKLFRIKI
NQIQMKETVE EQVSTTERVF QDRQYQIDAA IVRIMKMRKT LGHNLLVSEL YNQLKFPVKP
GDLKKRIESL IDRDYMERDK DNPNQYHYVA
//
