ID L7UB10_MYXSD Unreviewed; 687 AA.
AC L7UB10;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=MYSTI_03942 {ECO:0000313|EMBL:AGC45248.1};
OS Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=1278073 {ECO:0000313|EMBL:AGC45248.1, ECO:0000313|Proteomes:UP000011131};
RN [1] {ECO:0000313|EMBL:AGC45248.1, ECO:0000313|Proteomes:UP000011131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14675 / JCM 12634 / Mx s8
RC {ECO:0000313|Proteomes:UP000011131};
RX PubMed=23516218; DOI=10.1128/genomeA.00100-13;
RA Huntley S., Kneip S., Treuner-Lange A., Sogaard-Andersen L.;
RT "Complete genome sequence of Myxococcus stipitatus strain DSM 14675, a
RT fruiting myxobacterium.";
RL Genome Announc. 1:E0010013-E0010013(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP004025; AGC45248.1; -; Genomic_DNA.
DR RefSeq; WP_015349508.1; NC_020126.1.
DR AlphaFoldDB; L7UB10; -.
DR STRING; 1278073.MYSTI_03942; -.
DR KEGG; msd:MYSTI_03942; -.
DR PATRIC; fig|1278073.3.peg.4016; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_024627_0_0_7; -.
DR OrthoDB; 9805967at2; -.
DR Proteomes; UP000011131; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AGC45248.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 451..671
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 687 AA; 74772 MW; A6C350244333F555 CRC64;
MKYLCISANP HHPVAEELRR QGQEVLVLGS AAEADAELVN GRADVLVVEA ASLVQDARWL
DTLRGRARPW EPLVLGLAER ATDEDLSPLL SAGVDDFLVA PFPAEQVRAR GVLLERRAAL
RRRNQSSQAA ARGEMERLAS IIQTQSDVAL AGLDLAGVMR LLCERAQVLC GADGAAVALL
DDGFVDYRVA TGSLWPYKEF RLKMEGSLTG SSLQRGEVMR TDDTEEDARV NVRATRAVGA
RSMVCVPLWR EARPVGALNL VSQRVNAFDD RDVRTLELMA GLLGAAMGNA AEVEARHALM
DERAAALTAL QESQALFAAF MNHSPAVAYM KEEGGRRIWV NQPYRRFFGL PDDASLDRLD
DMNLMPETSA EHVRKEDQAV LDSGRPSVTE GMIPSPDGSD RHWLTYRFIV NEHSGRRLLG
GVALDITDRK AMQAQLVVAD RLAAVGTLAA GVAHEINNPL AFVLSNLSFL AVELQSVARE
LPLGRTSEME EVLREAVDGA HRVRQIVRDL RTFSRGDDEA AAAVNLQAVL ESAITMARGE
LKMRAQIIRD YRDVPPVEGN EGRFGQVFLN LLINAAHAIP EGKPESHQVR VVLRSTEDQV
IVEVHDTGVG MAPEVRARIF DPFFTTKPVG EGTGLGLSIC HGIVTGFGGE ISVESEPGRG
SVFRVTLPVG PRSRELGPPS PRLHLAG
//
