ID L7UBH9_MYXSD Unreviewed; 1739 AA.
AC L7UBH9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:AGC46256.1};
GN OrderedLocusNames=MYSTI_04968 {ECO:0000313|EMBL:AGC46256.1};
OS Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=1278073 {ECO:0000313|EMBL:AGC46256.1, ECO:0000313|Proteomes:UP000011131};
RN [1] {ECO:0000313|EMBL:AGC46256.1, ECO:0000313|Proteomes:UP000011131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14675 / JCM 12634 / Mx s8
RC {ECO:0000313|Proteomes:UP000011131};
RX PubMed=23516218; DOI=10.1128/genomeA.00100-13;
RA Huntley S., Kneip S., Treuner-Lange A., Sogaard-Andersen L.;
RT "Complete genome sequence of Myxococcus stipitatus strain DSM 14675, a
RT fruiting myxobacterium.";
RL Genome Announc. 1:E0010013-E0010013(2013).
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DR EMBL; CP004025; AGC46256.1; -; Genomic_DNA.
DR RefSeq; WP_015350512.1; NC_020126.1.
DR STRING; 1278073.MYSTI_04968; -.
DR KEGG; msd:MYSTI_04968; -.
DR PATRIC; fig|1278073.3.peg.5041; -.
DR eggNOG; COG1020; Bacteria.
DR eggNOG; COG2141; Bacteria.
DR eggNOG; COG3319; Bacteria.
DR HOGENOM; CLU_000022_2_13_7; -.
DR OrthoDB; 9757540at2; -.
DR Proteomes; UP000011131; Chromosome.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 3.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.20.20.30; Luciferase-like domain; 1.
DR Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR024011; Biosynth_lucif-like_mOase_dom.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR011251; Luciferase-like_dom.
DR InterPro; IPR036661; Luciferase-like_sf.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR020802; PKS_thioesterase.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR001031; Thioesterase.
DR InterPro; IPR041464; TubC_N.
DR InterPro; IPR044894; TubC_N_sf.
DR NCBIfam; TIGR04020; seco_metab_LLM; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00296; Bac_luciferase; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR Pfam; PF18563; TubC_N; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM00824; PKS_TE; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF51679; Bacterial luciferase-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1387..1462
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1739 AA; 192364 MW; C41D6AC50F64E18A CRC64;
MIAGELVAEL SRQGITLWVE GERLKYRAPK GALSPEALSL LSTHKDALVN HLRQDAADGE
SIHPLSHGQQ ALWFVAQLAP DSIAYNTALS LRIVTEVDVP ALRRACQRLV ERHGVLRTTF
GTRRGQPVQK VRRRDSLCFE HVLATDEEPE ALRARVTRAY EAPFDLEQGP LMRVHLFSRT
AREHVLLIAI HHIVYDGWSL LILGEELLRH LYPAEKAGVP AALPAPRATY TDYVRWQSEM
LAGATGQRLW DYWSKQLAGA PSSLDLPFAK PRPSVQTYAG ASVPVLLRGT LPRQLRAICE
QEGVTLYTLL LAAYLVLLHR YSGQEDLLVG SPSLGRTQPE FAKVVGNFMN MVVLRGDLSG
DPVFRDLLRQ LRQTVVGALA HQDFPFHLLV EKLNPERHAD RSPLFQAVFM LQPTPKGDIY
QGAAAGGLVL RPFDLPQQQG QFDLSLELSE TEDSLGGVLK FRTDLFDEAQ ALRMVGHLTT
LLEAIVESRD QRVSDLPLLT SEERREVLET WNDTSTEGPV REVCIHGLFE EQVQRTPDTV
ALISGRERLS YRELDLQANR LAHRLRALGV GPEVRVGLCV SRGAGMVVGM LGILKAGGAY
VPMDPTYPAE RLAYMLTDSR APVVVSESRL RVLPEDARVK VVWLDAEEPA AEEPPSSGVG
AENVAYTLYT SGSTGRPKAV LVCHRNIERF FAAMDDALEG TSPGVWLATT SMSFDISVLE
LLYSLTRGFQ VVLRGEQGVG RKPVSREGSR KPLEFSLFYF ASDEREHARD KYRLLLEGAR
FADAHGFTAV WTPERHFHAF GGLYPNPSVV SAALAATTRN IRLRAGSIVL PLHNPIRVAE
EWAVVDNLSG GRVDLSFASG WHPNDFVLAP ERFADARSQF FEQVALVRKL WKGDAVSFRN
GQGQDVRVQS QPRPIQPEVP VWVTAAGNPE TFRAAGEAGA SVLTHLLGQN LPELSKKLQL
YRAAWKSAGH GPGRGHVTLM LHTFMGEDVE AVRQKVDAPL RQYLKSSLGL LRSVIGPLPH
GEALESLSEE DVDLLLSRAV DRYFHQMGLF GDVESCLPLL EKLRELGVDE VACLIDFGVD
VESTLAGLHT LAALKERCQP SEAPEDDIPT LIARHGVTHF QCTPSMLRML LLEPEGAESL
RPLEKLLVGG EPFPVALARQ VLEHVEGDVL NMYGPTETTI WSSFDGVRDG DVGVTIGRPI
ADTRMYVLDP RLRPVPLGVP GEVFIGGEGV ARGYLHRPEL TAERFMPDPW GTRPGDRMYR
TGDLARHAAD GRIEFLGRLD TQVKVRGVRI ELGEIEAALR RHPDVPQAVV VARPDAAGEV
SLIAYVVTNV SPSELSRRLR EQLPASMIPA HFVQLEALPM TPNQKLDVRA LPLPDAPARE
VSAAYVAPRD ALELELVSLW EELFDLRPIG VTSGFFALGG HSLLAVRLMS RLRARFGRPL
PVSLLFQADT IQDLADLLRR QEGGARVREP LVRIQETGDK PPLFFVHPTG GDVLCYAPLS
RQLGPRQPFF ALQALMDSDS CSVEEMAARY LEEVRRVRPS GPYRLGGWST GGIVAQAMAR
QLEATGEHVE LLVLLETWSP ELYQRAQEPG ALMAWFATDL LGGTAAARLD PARLESLDEG
GRLRYLVEHA KALGALPGVE LPELEQRFRV FERNARALAR YRPEPYAGRV LFLQAEQLIA
NREEPMPAPA ESWGERLSQA RMQRVPGNHY TMLQAPYVRE VADRMAVVLE ELGAPVAAR
//
