ID L7UGC9_MYXSD Unreviewed; 324 AA.
AC L7UGC9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:AGC45484.1};
GN OrderedLocusNames=MYSTI_04184 {ECO:0000313|EMBL:AGC45484.1};
OS Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=1278073 {ECO:0000313|EMBL:AGC45484.1, ECO:0000313|Proteomes:UP000011131};
RN [1] {ECO:0000313|EMBL:AGC45484.1, ECO:0000313|Proteomes:UP000011131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14675 / JCM 12634 / Mx s8
RC {ECO:0000313|Proteomes:UP000011131};
RX PubMed=23516218; DOI=10.1128/genomeA.00100-13;
RA Huntley S., Kneip S., Treuner-Lange A., Sogaard-Andersen L.;
RT "Complete genome sequence of Myxococcus stipitatus strain DSM 14675, a
RT fruiting myxobacterium.";
RL Genome Announc. 1:E0010013-E0010013(2013).
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
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DR EMBL; CP004025; AGC45484.1; -; Genomic_DNA.
DR RefSeq; WP_015349744.1; NC_020126.1.
DR AlphaFoldDB; L7UGC9; -.
DR STRING; 1278073.MYSTI_04184; -.
DR KEGG; msd:MYSTI_04184; -.
DR PATRIC; fig|1278073.3.peg.4256; -.
DR eggNOG; COG0119; Bacteria.
DR HOGENOM; CLU_022138_3_2_7; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000011131; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:AGC45484.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 21..288
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 324 AA; 34549 MW; 5956027C9C50AFFA CRC64;
MAETPHSRAR GTLLGQLPKQ VEVYEVGPRD GLQNELRTLP TRDKARLIDA LVSAGEKRIE
VTSFVSPKWI PQLADAEELL KLVGRREGVV FSALVPNLKG LERAKDAGLE EAAVFISASE
AHSKKNINKT IAEAMASARE VTGAALQAGM RVRGYLSTVW GCPYEGHVPV ERVVDICRYL
VDAGIYQLSL GDTIGVGTPR QTEEILGALL QHIPVEKLAL HLHDTRGTAL ANSLVGLAAG
VTTFDASIGG LGGCPYAPGA AGNLATEDAV FMFHGMGVDT GINLDRLVEA GEIAQELIGR
KLAGKYLQAA LGEREKKASR RAQT
//
