ID L7UMQ4_MYXSD Unreviewed; 561 AA.
AC L7UMQ4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=MYSTI_07565 {ECO:0000313|EMBL:AGC48837.1};
OS Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=1278073 {ECO:0000313|EMBL:AGC48837.1, ECO:0000313|Proteomes:UP000011131};
RN [1] {ECO:0000313|EMBL:AGC48837.1, ECO:0000313|Proteomes:UP000011131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14675 / JCM 12634 / Mx s8
RC {ECO:0000313|Proteomes:UP000011131};
RX PubMed=23516218; DOI=10.1128/genomeA.00100-13;
RA Huntley S., Kneip S., Treuner-Lange A., Sogaard-Andersen L.;
RT "Complete genome sequence of Myxococcus stipitatus strain DSM 14675, a
RT fruiting myxobacterium.";
RL Genome Announc. 1:E0010013-E0010013(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP004025; AGC48837.1; -; Genomic_DNA.
DR AlphaFoldDB; L7UMQ4; -.
DR STRING; 1278073.MYSTI_07565; -.
DR KEGG; msd:MYSTI_07565; -.
DR PATRIC; fig|1278073.3.peg.7690; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_114_44_7; -.
DR OrthoDB; 5481641at2; -.
DR Proteomes; UP000011131; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43711:SF33; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AGC48837.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:AGC48837.1}.
FT DOMAIN 4..48
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 328..545
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 561 AA; 60158 MW; 392886C9AE40FBE5 CRC64;
MSETLAPFAS AFEALPDPAY VLDAQGRILT CSTAGARAFG RGPESLTGLH WSELGIPAED
IARLEAARAL TLARGCCVTE ELPWPVDTGL RRHSVVLTPL PDGTVLVTAR PLTEAEAVYS
RALELEQASR AEVEQAERRR SFLYQAMTTL FTHPPDPHGM YTLLAHLAVP DLADWCLVDA
LEQGPWVSRV AVACLDPTQR ERAGDLPDRI ELHDDAPVGL LRVLRTGEPE LVPAVTDSLL
RAAASEPAHP ALLLTLQARS YMIVPLRARG HTLGAVTFVS SGSGRRYGPE DLALAEDLCL
RASLAIDNAR LVGESRRAAR AREDLLAVVS HDLKNPLGVV QLGAALLARG PGAKPGGEVV
AKQATRIQDA TDRMSRLISD LLDWGRLEAG GLPLDLREHS MTALLTEATE SIRPLAEAKG
LHLYTQPPED DVRVRCDRTR VLQVLGNLMG NAVKFTPSGG DLEVGASVRD GLVCIHVRDT
GDGIAAEALP HIFDRYWQAR DATSRGTGLG LAIAKGLVEA HGGHIHARST RGEGSTFAFT
LPLVGVSTAP HSTRSRPRLD A
//
