ID   L8FSQ0_PSED2            Unreviewed;       710 AA.
AC   L8FSQ0;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0000259|Pfam:PF00501};
GN   ORFNames=GMDG_05682 {ECO:0000313|EMBL:ELR02736.1};
OS   Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS   white-nose syndrome fungus) (Geomyces destructans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR02736.1, ECO:0000313|Proteomes:UP000011064};
RN   [1] {ECO:0000313|Proteomes:UP000011064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Geomyces destructans 20631-21.";
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL573293; ELR02736.1; -; Genomic_DNA.
DR   RefSeq; XP_012744113.1; XM_012888659.1.
DR   AlphaFoldDB; L8FSQ0; -.
DR   STRING; 658429.L8FSQ0; -.
DR   VEuPathDB; FungiDB:GMDG_05682; -.
DR   HOGENOM; CLU_000022_45_4_1; -.
DR   InParanoid; L8FSQ0; -.
DR   OrthoDB; 443463at2759; -.
DR   Proteomes; UP000011064; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43272:SF3; LONG-CHAIN-FATTY-ACID--COA LIGASE 5; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011064}.
FT   DOMAIN          69..514
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   710 AA;  77746 MW;  E6A3AC8330AB0806 CRC64;
     MSTAFHLTKD QDANYKQLAS PPPGLKPYSV ALPGTAIEGR SAVYRHWKFQ SGPLFSTIDP
     SLHTAHDVFE ASAKKYAGRR CLGQRGYDAA KKTWGKYTWE TYAQVAERRR NFGAGVVELH
     KGVGVTGDKY GVGLWCQNRP EWQIADLGCM SQSLFTVSIY DTLGPETTEY IINHAGLACV
     VTSLPHIPLL LKLAPRVPSM KLIICLDPLN GADKPGNSMA ELLNTLGKEV GVAIHYIGDV
     EELGAKSSIP MNPPQPDDII TINYTSGTTG NPKGVVLTQA NALAAVSTGR FVSHGTPNDI
     VMSYLPLAHI YERVTEGGAL LCGSSIGYFC GDIVGLVDDM KELKPTGFVS VPRLYNRFGG
     AIRSQALEAE GLKGVMGRHV VNTKLANLRK PEGEATVFHA VYDRLYTPKL RSAFGLQNSK
     RMVSGSAPID PQLHTLLRAA FGNPIKQGYG MTETYAIGSC QMDSDTSTGN SGGVLPSVEV
     CLSSVPDMEY LVTDKPNPRG ELLVKTTALF REYYRDPAET AKAMTSDGWF KTGDIAEIDS
     RGRIKIVDRV KNLLKLAQGE YVSPERLENV YLANTNLANI AFVHGDSTEA FLVSVFGVDP
     MAFAPFASAI LKKSIDPLDA AAVREACKDQ RVTRAFLVEL EKIGKKAQFN NWERVRKVHL
     ALEPFSIDNE TLTPTLKMKR PKVAKMFRDE LDRMYAEALE EEKSKSKPRL
//