ID L8G793_PSED2 Unreviewed; 442 AA.
AC L8G793;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:ELR08987.1};
GN ORFNames=GMDG_00605 {ECO:0000313|EMBL:ELR08987.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR08987.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL573174; ELR08987.1; -; Genomic_DNA.
DR RefSeq; XP_012738998.1; XM_012883544.1.
DR AlphaFoldDB; L8G793; -.
DR STRING; 658429.L8G793; -.
DR VEuPathDB; FungiDB:GMDG_00605; -.
DR HOGENOM; CLU_035565_0_0_1; -.
DR InParanoid; L8G793; -.
DR OrthoDB; 245129at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF1; ZGC:77287; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|EMBL:ELR08987.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:ELR08987.1};
KW Transferase {ECO:0000313|EMBL:ELR08987.1}.
FT DOMAIN 206..442
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 239
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 442 AA; 48668 MW; CB384BECB2AD89FC CRC64;
MQSLEGLRSG EYRGTKRLKI PSGIVTFPRE IFKLSRSLEI LDLSGNSSLS ELPSDFGRLH
NLKIAFFSDC SFTAFPKQLA ECRSLEMVAF KGNGMKTIPE GSLPPNLRWL ILTNNLIEEL
PRSIGQCHRL QKCMLAGNQL KSLPEEMANC KKLGLLRLSA NKLEGLPTWL FTMPELSFMA
FAGNPCLQTE TVIDNPVLSL VAWEELQVKE LLGEGASGVI SRGLWTTSAD SKAKQVAVKL
FKGEVTSDGS PIDEMAACIA AGTHSNLIST IGKVHGHPNE QRGLVLELIP PHFENLGLPP
SLQTCTRDNF TPGKYFTIQK CKNILVSIAS AAAHLHKSGI THGDLYAHNI LIDEAGHALL
GDFGAATVYS KTHVHSEAIE KLEVYAFGHL IEDMLSLLDP EVFGEKEAFI EEELNELHYR
CTRPVVKDRP LFQGILEELN GL
//
