ID L8HYR9_9CETA Unreviewed; 246 AA.
AC L8HYR9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Transcription factor A, mitochondrial {ECO:0000256|ARBA:ARBA00040582};
GN ORFNames=M91_00401 {ECO:0000313|EMBL:ELR48454.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR48454.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR48454.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid
CC {ECO:0000256|ARBA:ARBA00004436}.
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DR EMBL; JH882717; ELR48454.1; -; Genomic_DNA.
DR RefSeq; XP_005906647.1; XM_005906585.2.
DR AlphaFoldDB; L8HYR9; -.
DR SMR; L8HYR9; -.
DR STRING; 72004.ENSBMUP00000009097; -.
DR Ensembl; ENSBMUT00000010598; ENSBMUP00000009097; ENSBMUG00000007087.
DR GeneID; 102274331; -.
DR KEGG; bom:102274331; -.
DR CTD; 7019; -.
DR OrthoDB; 5472820at2759; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR GO; GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR GO; GO:0001018; F:mitochondrial promoter sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0034246; F:mitochondrial transcription factor activity; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0006391; P:transcription initiation at mitochondrial promoter; IEA:Ensembl.
DR CDD; cd21987; HMG-box_TFAM_rpt2; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 2.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR48112; HIGH MOBILITY GROUP PROTEIN DSP1; 1.
DR PANTHER; PTHR48112:SF38; TRANSCRIPTION FACTOR A, MITOCHONDRIAL; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF09011; HMG_box_2; 1.
DR SMART; SM00398; HMG; 2.
DR SUPFAM; SSF47095; HMG-box; 2.
DR PROSITE; PS50118; HMG_BOX_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080}.
FT DOMAIN 50..118
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 155..219
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 50..118
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 155..219
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
SQ SEQUENCE 246 AA; 28830 MW; 4ACBD828578734B7 CRC64;
MALLRGVWGV LNALGKSGAD LCAGCGSRLR SPFSFAYVPK WFSSSLSGYP KKPMTSYVRF
SKEQLPIFKA QNPDAKNSEL IKKIAKLWRE LPDSEKKIYE DAYRADWQVY KEEINRIQEQ
LTPSQMVSLE KEIMQKRLKK KALIKKRELT MLGKPKRPRS AYNIFIAERF QEARDGTSQV
KLKAINENWK NLSNSQKQVY IQLAKDDKIR YYNEMKSWEE QMMEVGREDL IRRSIKYPAK
NDPEKF
//
