ID L8I7Q5_9CETA Unreviewed; 395 AA.
AC L8I7Q5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=RAB6-interacting golgin {ECO:0000256|ARBA:ARBA00014130};
DE AltName: Full=N-terminal kinase-like-binding protein 1 {ECO:0000256|ARBA:ARBA00033032};
DE AltName: Full=SCY1-like 1-binding protein 1 {ECO:0000256|ARBA:ARBA00032512};
GN ORFNames=E5288_WYG004978 {ECO:0000313|EMBL:MXQ81906.1}, M91_03739
GN {ECO:0000313|EMBL:ELR51569.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR51569.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR51569.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080}, and YakQH1
RC {ECO:0000313|EMBL:ELR51569.1};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
RN [2] {ECO:0000313|EMBL:MXQ81906.1, ECO:0000313|Proteomes:UP000322234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WY2019 {ECO:0000313|EMBL:MXQ81906.1};
RC TISSUE=Blood {ECO:0000313|EMBL:MXQ81906.1};
RA Liu Y.;
RT "The sequence and de novo assembly of the wild yak genome.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GORAB family.
CC {ECO:0000256|ARBA:ARBA00005599}.
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DR EMBL; JH881963; ELR51569.1; -; Genomic_DNA.
DR EMBL; VBQZ03000009; MXQ81906.1; -; Genomic_DNA.
DR RefSeq; XP_005902452.1; XM_005902390.1.
DR AlphaFoldDB; L8I7Q5; -.
DR STRING; 72004.ENSBMUP00000028268; -.
DR Ensembl; ENSBMUT00000032579; ENSBMUP00000028268; ENSBMUG00000021185.
DR GeneID; 102274684; -.
DR KEGG; bom:102274684; -.
DR CTD; 92344; -.
DR OrthoDB; 5358019at2759; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR Proteomes; UP000322234; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR GO; GO:1905515; P:non-motile cilium assembly; IEA:Ensembl.
DR GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR InterPro; IPR007033; GORAB.
DR PANTHER; PTHR21470:SF2; RAB6-INTERACTING GOLGIN; 1.
DR PANTHER; PTHR21470; RAB6-INTERACTING PROTEIN GORAB; 1.
DR Pfam; PF04949; Transcrip_act; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080}.
FT REGION 1..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 246..306
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 35..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 395 AA; 45206 MW; 7D67B229FEA4BD49 CRC64;
MCLGSRVGSR GSKVWGTRRA GKPRRMAQGW AGFSEEELRR LKQTKDPFEP QQRLPGKKSR
QQLQRERALQ EQSQKFGLQD GPTSLPPEQL LSAPKQRFNT QRPYSSPPTP LILTSPVGDG
KPQGTESQQK ELGLKSSHEV HKNAEVLPLK ADCQLEKKKV ELQEKSRWEV LQQEQRLMEE
KNKRKKALLA KAIAERSKRT QAETMKLKRI QKELQALDDM VSADIGILRN RIDQASLDYS
YARKRFDRAE AEYVTAKLEL QRKTELKEQL TEHLCTIIQQ NELRKAKKLE ELMQQLDVHA
DEETLELEVE VERLLCEQEA EARKRVVHLE RSFQPSGESV TLELAKENKK PQDQAASPKV
DEQGKNSNSI ALLDPERPNQ EVETAVKDIS ASLIT
//
