ID L8IJ75_9CETA Unreviewed; 397 AA.
AC L8IJ75;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Matrilin-3 {ECO:0000313|EMBL:ELR56371.1};
DE Flags: Fragment;
GN ORFNames=M91_00104 {ECO:0000313|EMBL:ELR56371.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR56371.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR56371.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; JH881124; ELR56371.1; -; Genomic_DNA.
DR AlphaFoldDB; L8IJ75; -.
DR STRING; 72004.ENSBMUP00000007066; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF12; MATRILIN-3; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080}.
FT DOMAIN 10..185
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 191..232
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 233..274
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 317..358
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ELR56371.1"
FT NON_TER 397
FT /evidence="ECO:0000313|EMBL:ELR56371.1"
SQ SEQUENCE 397 AA; 43557 MW; 0F9DD7E5D3CD26CE CRC64;
AGVCKSRPLD LVFIIDSSRS VRPLEFTKVK TFVSKIIDTL DIGPMDTRVA VVNYASTVKI
EFHLQTHSDK QSLKRAVARI TPLSTGTMSG LAIQTAMDEA FTVEAGARGP SSNIPKVAII
VTDGRPQDQV NEVAARARAS GIELYAVGVD RADMESLKMM ASEPLDEHVF YVETYGVIEK
LSSRFQETFC ALDPCALGTH QCQHVCISDG EGRHHCECSQ GYSLNADKKT CSAIDKCALN
THGCEHICVN DRTGSYHCEC YEGYTLNEDR KTCSAQDQCA LGTHGCQHIC VNDRAGSHHC
ECYEGYTLNE DKKTCSVLNQ CALGSHGCQH ICVYDGNASY HCDCDTGYTL NEDKKTCSAI
EEARRLISTE DACACEATLA FQDKVNSYLQ RLNSKHI
//
