ID L8INE8_9CETA Unreviewed; 345 AA.
AC L8INE8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Sorting nexin-15 {ECO:0000313|EMBL:ELR57568.1};
GN ORFNames=E5288_WYG016092 {ECO:0000313|EMBL:MXQ90658.1}, M91_15962
GN {ECO:0000313|EMBL:ELR57568.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR57568.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR57568.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080}, and YakQH1
RC {ECO:0000313|EMBL:ELR57568.1};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
RN [2] {ECO:0000313|EMBL:MXQ90658.1, ECO:0000313|Proteomes:UP000322234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WY2019 {ECO:0000313|EMBL:MXQ90658.1};
RC TISSUE=Blood {ECO:0000313|EMBL:MXQ90658.1};
RA Liu Y.;
RT "The sequence and de novo assembly of the wild yak genome.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH880973; ELR57568.1; -; Genomic_DNA.
DR EMBL; VBQZ03000064; MXQ90658.1; -; Genomic_DNA.
DR RefSeq; XP_005894136.1; XM_005894074.2.
DR AlphaFoldDB; L8INE8; -.
DR SMR; L8INE8; -.
DR STRING; 72004.ENSBMUP00000004730; -.
DR Ensembl; ENSBMUT00000005492; ENSBMUP00000004730; ENSBMUG00000003708.
DR GeneID; 102286466; -.
DR KEGG; bom:102286466; -.
DR CTD; 29907; -.
DR OrthoDB; 5476410at2759; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR Proteomes; UP000322234; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd02677; MIT_SNX15; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR007330; MIT_dom.
DR InterPro; IPR036181; MIT_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR15508:SF8; LD24550P; 1.
DR PANTHER; PTHR15508; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR Pfam; PF04212; MIT; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00745; MIT; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF116846; MIT domain; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011080}.
FT DOMAIN 1..130
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 133..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..157
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 345 AA; 38403 MW; 56C0009501B6BE25 CRC64;
MSRQAKDDFL RHYTVSDPRT HPKGYTEYKV TAQFISKRDP EDVKEVVVWK RYSDFRKLHG
DLAYTHRNLF RRLEEFPAFP RGQVFGRFEA SVIEERRKGA EDLLRFTVHI PALNNSPQLK
EFFRGGEVTR PSEVSGDLHI LPPPLIPTPP PDEPRVQPHE TWLPQPLPAE RRGLEELEVP
ADPPPSSPAQ EALDLLFNCG STEEASSSPA RGPLTEAELA LFDPFSKEEG AGPSPTHIGE
LAALEAGSGR PDQEPWEPGG QAEEDDEEGE PAPAYLSQAT ELITQALRDE KAGAYPAALQ
GYRDGVHILL QGVPGDPSPA RREGVKKKAA EYLKRAEEIL HLHLS
//
