ID L8IWI0_9CETA Unreviewed; 379 AA.
AC L8IWI0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Fibroblast growth factor receptor-like 1 {ECO:0000313|EMBL:ELR60811.1};
DE Flags: Fragment;
GN ORFNames=M91_12918 {ECO:0000313|EMBL:ELR60811.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR60811.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR60811.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
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DR EMBL; JH880544; ELR60811.1; -; Genomic_DNA.
DR AlphaFoldDB; L8IWI0; -.
DR STRING; 72004.ENSBMUP00000033022; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05856; IgI_2_FGFRL1-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR19890; FIBROBLAST GROWTH FACTOR RECEPTOR; 1.
DR PANTHER; PTHR19890:SF10; FIBROBLAST GROWTH FACTOR RECEPTOR-LIKE 1; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:ELR60811.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 353..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..93
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 125..215
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 224..332
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 96..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ELR60811.1"
FT NON_TER 379
FT /evidence="ECO:0000313|EMBL:ELR60811.1"
SQ SEQUENCE 379 AA; 41475 MW; 1B8AC7A4B0841925 CRC64;
LTPAGPPRMA DKVVPRQVAR LGRTVRLQCP VEGDPPPLTM WTKDGRTIHG GWSRFRVLPQ
GLKVKEVEPE DAGAYVCKAT NGFGSLSVNY TLIVMDDTSP GRESPGHDSS SGGQEDPASK
QWARPRFTQP SKMRRRVIAR PVGSSVRLKC VASGHPRPDI MWMKDDQALT RPEAGEHRKK
KWTLSLKNLR PEDSGKYTCR VSNRAGAINA TYKVDVIQRT RSKPVLTGTH PVNTTVDFGG
TTSFQCKVRS DVKPVIQWLK RVEYGAEGRY NSTIDVGGQK FVVLPTGDVW SRPDGSYLNK
LLITRARQDD AGMYICLGAN TMGYSFRSAF LTVLPDPKPP GPPVAPSSST TSLPWPVVIG
IPAGAVFIVG TVVLWLCQA
//
